|AFMR Website||Meetings/Events Calendar||Submit a JIM manuscript|
Janice P. Dutcher, MD
Virtual Education Series
Our Virtual Education Portal is the source for AFMR’s new online initiative, including the newly launched Virtual Education Series. Our first offering - How to Write a Manuscript - was a great success. Don’t miss our October and November presentations!
Richard W. McCallum, MD
The workshop was led by Richard McCallum, MD, Editor-in-Chief of the Journal of Investigative Medicine (JIM). Dr. McCallum is Professor of Medicine in the Division of Gastroenterology at Texas Tech University Health Sciences Center.
The seminar consisted of four (4) sections of about 15 minutes on:
An audio of the workshop will be available on the Virtual Education Portal soon.
Submit a manuscript to the Journal of Investigative Medicine (JIM). There are no page charges for AFMR members’ published manuscripts.
AFMR continues its newly launched Virtual Education Series with two fall events:
With in-person meetings being cancelled or in limbo, the AFMR Virtual Education Series will offer a range of events — from workshops to symposia to abstract/journal review sessions. AFMR hopes to continue the series once in-person meeting return.
Theo Trandafirescu, MD
|Date:||Tuesday, October 20, 2020|
|Duration:||6:00 pm - 7:00 pm ET|
|Lead:||Theo Trandafirescu, MD — Eastern Region Council Chair|
Associate Professor of Medicine at Icahn School of Medicine; Mount Sinai Queens Hospital Center
Join Dr. Trandsfirescu and a panel of experts —Tracey O'Brien, Sofia Lakhdarand and Akwe Nyabera — as they take a deep dive into three clinical cases in the following subject areas:
Allison B. Reiss, MDD
|Date:||Wednesday, November 4, 2020|
|Duration:||Noon - 1:00 pm ET|
|Lead:||Allison B. Reiss, MD — AFMR National Council Councilor-at-Large Associate Professor of Medicine, New York University Long Island School of Medicine Member, Alzheimer's Foundation of America's Medical, Scientific and Memory Screening Board Editorial Board member, Journal of Investigative Medicine (JIM) and Journal of Investigative Medicine High-Impact case Reports (JIM-HICR)|
In this webinar, Dr. Reiss will discuss past Alzheimer’s disease treatment disappointments and ways in which, they may lead to future breakthroughs for preventing and slowing neuronal cell death using innovative approaches.
Alzheimer's disease (AD) is the most common cause of progressive dementia, resulting in irreversible deterioration of brain function, cognition and memory. It is considered the sixth leading cause of death in the world. The global burden of AD is enormous and as the number of older persons increases over the next few decades, the number of AD cases is expected to skyrocket. Amyloid plaques and tau tangles are characteristic of AD. However, immunotherapy using antibodies which bind to amyloid or tau to promote their clearance has not proven effective as a therapy thus far. Researchers are struggling to develop ways to stop disease progression before people develop deficits in thinking and changes in personality.
Researchers around the world are racing to develop therapeutics and vaccines aimed at stemming the coronavirus pandemic.
Submit your abstracts to the 2021 AFMR Eastern Regional Meeting and Midwest Clinical & Translational Research Meeting.Everyone is eligible to submit abstracts to these two events, which will be virtual due to uncertainties of the COVID 19 pandemic. Join AFMR to be eligible for awards.
Check back for more information. Deadline: Sunday, January 10 2021, 11:59 CST.
Ricardo Correa, MD
The list was created in honor of National Hispanic Heritage Month, which runs from September 15 - October 15, 2020.
“This list — selected based on scholarly achievements, mentoring excellence, and commitment to diversity, equity, and inclusion — represents only a subset of the scientific role models in the community,” CELLMentor explained. “Our aim in assembling these names is to put an end to the harmful myth that there are not enough diverse scientists to give seminars, serve as panelists, or fill scientific positions. We highlight scientists encompassing careers within academia, government, and biotech and showcase individuals committed to serving diverse student populations at Hispanic-serving institutions.”
Dr. Correa is Program Director for Endocrinology, Diabetes and Metabolism Fellowship and the Director for Diversity of Graduate Medical Education, University of Arizona College of Medicine-Phoenix.
In honor of Hispanic Heritage Month, this podcast discusses health disparities in the Latinx community during COVID-19 with Omar Matuk, MD of the University of Houston College of Medicine and Ilan Shapiro, MD of AltaMed Health Services.
They are interviewed by Ricardo Correa, MD, AFMR Western Region Secretary-Treasurer and National Council member.
Dr. Matuk is a clinical assistant professor of pediatrics at the University of Houston College of Medicine. In addition, he is responsible for the pediatric pre-clinical and clinical curriculum and is developing a direct primary care model for the uninsured population.
Dr. Shapiro is Medical Director of Medical Education and Wellness at AltaMed, which serves more than 300,000 community residents in Southern California. AltaMed works to eliminate disparities in healthcare access and outcomes by providing quality health and human services to Latino, multiethnic and unserved communities.
The AFMR mission is to develop and mentor tomorrow's leaders in medical research. The National Council wants AFMR early investigators to know about the important opportunity from NIH — the Early Career Reviewer (ECR) Program.
To help early career scientists become more competitive as grant applicants through first-hand experience with peer review while enriching and diversifying the CSR pool of trained reviewers.
||Journal of Investigative Medicine|
|American Federation for Medical Research|
Physician-scientist and the COVID-19 dilemma
Richard McCallum 10.1136/jim-2020-001582
Faculty Development & Education
Saving the endangered physician-scientists: reintroducing them to an environment of administrative support
Shreya Shah, Oliver Luc Villemain 10.1136/jim-2020-001544
Interventions to improve medication adherence in adolescents with HIV: a systematic review and meta-analysis
Sasha Alcon, Billal Ahmed, David Sloane, Youn Seon Lim, Joseph Steven Cervia 10.1136/jim-2020-001295
Psychosocial factors associated with symptoms of generalized anxiety disorder in general practitioners during the COVID-19 pandemic
Alvaro Monterrosa-Castro, Velia Redondo-Mendoza, María Mercado-Lara1 0.1136/jim-2020-001456
Diagnostic accuracy of time to first positivity of blood cultures for predicting severe clinical outcomes in children with pneumonia-related bacteremia
Yin Zhang, Jilei Lin, Qingxia Shi, Chulin Li, Jingyue Liu, Jihong Dai 10.1136/jim-2020-001473
Perinatal quality improvement bundle to decrease hypothermia in extremely low birthweight infants with birth weight less than 1000 g: single-center experience over 6 years
Dilip R Bhatt, Nirupa Reddy, Reynaldo Ruiz, Darla V Bustos, Torria Peacock, Roman-Angelo Dizon, Sunjeeve Weerasinghe, David X Braun, Rangasamy Ramanathan 10.1136/jim-2020-001334
Incidence of acute kidney injury and its association with mortality in patients with COVID-19; a meta-analysis
Panupong Hansrivijit, Chenchen Qian, Boonphiphop Boonpheng, Charat Thongprayoon, Saraschandra Vallabhajosyula, Wisit Cheungpasitporn, Nasrollah Ghahramani 10.1136/jim-2020-001407
Differential gene expression in patients with primary mitral valve disease: identifying potential therapeutic targets in the era of precision medicine
Emily Shih, John J Squiers, Jacob Turner, Michael DiMaio, William T Brinkman, Robert L Smith 10.1136/jim-2020-001467
A Case of Extracorporeal Membrane Oxygenation as a Salvage Therapy for COVID-19-Associated Severe Acute Respiratory Distress Syndrome: Mounting Evidence
Coronavirus disease 2019 (COVID-19) caused by a novel human coronavirus has led to a tsunami of viral illness across the globe, originating from Wuhan, China. Although the value and effectiveness of extracorporeal membrane oxygenation (ECMO) in severe respiratory illness from COVID-19 remains unclear at this time, there is emerging evidence suggesting that it could be utilized as an ultimate treatment in appropriately selected patients not responding to conventional care. We present a case of a 32-year-old COVID-19 positive male with a history of diabetes mellitus who was intubated for severe acute respiratory distress syndrome (ARDS). The patient’s hypoxemia failed to improve despite positive pressure ventilation, prone positioning, and use of neuromuscular blockade for ventilator asynchrony. He was evaluated by a multidisciplinary team for considering ECMO for refractory ARDS. He was initiated on venovenous ECMO via dual-site cannulation performed at the bedside. Although his ECMO course was complicated by bleeding, he showed a remarkable improvement in his lung function. ECMO was successfully decannulated after 17 days of initiation. The patient was discharged home after 47 days of hospitalization without any supplemental oxygen and was able to undergo active physical rehabilitation. A multidisciplinary approach is imperative in the initiation and management of ECMO in COVID-19 patients with severe ARDS. While ECMO is labor-intensive, using it in the right phenotype and in specialized centers may lead to positive results. Patients who are young, with fewer comorbidities and single organ dysfunction portray a better prognosis for patients in which ECMO is utilized.
Intravascular Large B-Cell Lymphoma Presenting as Acute Axonal Polyneuropathy: A Case Report and Literature Review
Intravascular large B-cell lymphoma (ILBL) is a rare and difficult to diagnose subtype of large B-cell lymphoma. The most common locations of presentation are in the central nervous system and the skin, but there are reports of other organ involvement. Due to the indolence, nonspecific symptoms, and rarity of the disease, this form of lymphoma is most often diagnosed postmortem. In this article, we describe a case of ILBL that presented as a rapidly progressive acute axonal polyneuropathy. Acute axonal polyneuropathy is a common disease process with a wide differential diagnosis, but there is limited literature on its prevalence as the presenting symptom of ILBL. This patient was treated with R-EPOCH and intrathecal methotrexate with significant improvement in his polyneuropathy after 1 cycle, and complete remission after 6 cycles. Data on chemotherapy regimens and their success rates for this disease are lacking.
Comparison of Genetic Variants and Manifestations of OTUD6B-Related Disorder: The First Mexican Case
The intellectual disability syndrome characterized by seizures and dysmorphic features was initially described in 2017 and was associated with genetic variants in the OTUD6B gene, identified by exome sequencing (ES) in a large cohort. This multisystem disorder primarily affects the central nervous system, the gastrointestinal, and the skeletal systems. In this article, we describe the first Mexican patient diagnosed by ES. The homozygous c.433C>T (p.Arg145*) variant of the OTUD6B gene confirmed this intellectual disability syndrome. In addition to seizures and other more frequently reported manifestations of this condition, this is the third patient with associated hypothyroidism and hypogammaglobulinemia, underscoring the value of screening for these conditions in other patients. The current challenge with this patient is to ensure medical management of his seizures and provide him with a better quality of life. The possibilities of additional therapeutic approaches may increase by understanding the physiopathology of the involved pathways.
The NIH Coronavirus Disease 2019 (COVID-19): Information for NIH Applicants and Recipients of NIH Fund page offers a wide range of guidance on research funding.
|The Guidance portion includes the following sections:
||In the Funding section, there are two sections:
The World Health Organization (WHO) has a dedicated page devoted to global research on coronavirus.
News and information on COVID-19 is constantly changing.
Johns Hopkins has updated and expanded its resource center.
The website now has separate pages covering:
Its Interactive Map is updated throughout the day.
|Dates have been set for AFMR Regional and Affiliate meetings for 2021. Meeting dates, locations, and abstract information are listed below based on date.
Visit the AFMR website to get the latest updates on 2021 AFMR Meetings & Events.
Cherry Wongtrakool, MD
VP of Meetings & Programs
Western Regional Meeting
January 29-30, 2021
Going Virtual for 2021
Southern Regional Meeting
February 25-27, 2021
Translational Science 2021
March 30, 2021-April 2, 2021
Eastern Regional Meeting
April 2, 2021
Midwest Clinical & Translational Research Meeting
April 8-9, 2021
Holiday Inn Mart Plaza, Chicago, Illinois
Abstract Deadline: January 10, 2021
|Experimental Biology 2021
May 1-4, 2021