Volume I, Issue 3: April 2020
American Federation for Medical Research (AFMR) Insights
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IN THIS ISSUE

 

The coronavirus public health crisis has impacted the AFMR Eastern and Midwest Regional meetings, as well as EB2020 and TS2020 — just as it has all elements of society. All four events, which were scheduled for the month of April, were cancelled. TS 2020 has scheduled virtual presentations. More

 
Coronavirus Resources

News and information on COVID-19 are constantly changing.

Here are quick links to resources for coronavirus updates: The Centers for Disease Control (CDC), Food and Drug Administration (FDA), Johns Hopkins Corona Virus Resource Center, and World Health Organization:

 

The Imperial College of London is the source of an analysis of the spread of COVID-19 and impact of various public health measures on its slowing and suppression. The Imperial College of London is the source of an analysis of the spread of COVID-19 and impact of various public health measures on its slowing and suppression. The findings were published in the 9th Report from the WHO Collaborating Centre for Infectious Disease Modelling. The research team works at the MRC Centre for Global Infectious Disease Analysis (MRC-GIDA) and the Abdul Latif Jameel Institute for Disease and Emergency Analytics (J-IDEA) at the Imperial College of London. Professor Neil Ferguson, head of the MRC GIDA team and J-IDEA director stated, "The world is facing the most serious public health crisis in generations". More

 

AFMR National Council member Dr. Allison B. Reiss, Associate Professor of Medicine at the New York University Long Island School of Medicine, has given a series of interviews offering advice to caregivers or Alzheimer's and dementia patients about how to protect their loved ones from the coronavirus. Dr. Reiss is a member of the Alzheimer's Foundation of America's Medical, Scientific and Memory Screening Board. AFMR National Council member Dr. Allison B. Reiss, Associate Professor of Medicine at the New York University Long Island School of Medicine, has given a series of interviews offering advice to caregivers or Alzheimer's and dementia patients about how to protect their loved ones from the coronavirus. Dr. Reiss is a member of the Alzheimer's Foundation of America's Medical, Scientific and Memory Screening Board. More

 

Federation of American Societies for Experimental Biology (FASEB) AFMR is a member of the Federation of American Societies for Experimental Biology (FASEB), which has been proactive with both resources and legislative advocacy in support of scientific societies in response to the coronavirus public health crisis. More

 
AFMR Publications Highlights

Journal of Investigative Medicine (JIM)

Journal of Investigative Medicine (JIM)

Editorial
Faculty Development/Mentoring Evolution of Mentorship in Academic Medicine
Samrat Das; 10.1136/jim-2020-001302

Podcast
Colorectal Cancer Screening in Young Patients
Dr. Nicholas Davidson, Professor of Medicine and Chief of Gastroenterology, Washington University School of Medicine. Hosted by JIM editor-in chief. Dr. Richard McCallum

Original Research
Relationship between Non-alcoholic Fatty Liver Disease During Pregnancy and Abnormal Glucose Metabolism During and After Pregnancy
Maryam Sattari, Fernando Bril, Robert Egerman, Srilaxmi Kalavalapalli, Kenneth Cusi ; 10.1136/jim-2019-001186

Original Research
Prediction of Emergency Cesarean Section by Measurable Maternal and Fetal Characteristics
Ping Guan, Fei Tang, Guoqiang Sun, Wei Ren; 10.1136/jim-2019-001175


JIM — High Impact Case Reports

JIM — High Impact Case Reports

Video-Assisted Thoracoscopic Lung Biopsy in Critically Ill Patients with Hematologic Malignancy and Acute Respiratory Distress Syndrome: A Case Series Report
In this article, we report a series of 8 critically ill patients with hematologic malignancies and ARDS, who underwent VATS lung biopsy, in a specialized institution in Cali, Colombia, from 2015 to 2019, with special emphasis on its diagnostic yield, modifications in treatment protocol, and safety. VATS lung biopsy is a minimally invasive procedure that appears to be a relatively safe with few postoperative complications and minimal perioperative mortality. It has a high diagnostic yield, resulting in a modification of treatment in a nondepreciable percentage of patients. However, this subset of patients was critically ill, with a high risk of mortality, and the lung biopsy did not appear to affect in this aspect. Future randomized controlled trials are needed to further clarify this topic.

Bacterial Endocarditis Caused by Actinomyces oris: First Reported Case and Literature Review
Actinomyces species are gram-positive, facultative anaerobic bacilli. Infection caused by Actinomyces species is usually limited to cervicofacial, thoracic, and abdominopelvic regions. Infective endocarditis due to Actinomyces species is extremely rare with only 30 reported cases since 1939. We report a case of Actinomyces oris endocarditis in a 14-year-old boy who had a 2-week history of dyspnea on exertion without other constitutional signs. Transthoracic echocardiography was suggestive of perforation of the right coronary cusp of aortic valve. No organisms were isolated from blood cultures. The patient underwent surgical valve repair due to deteriorated cardiac function. Valve tissue culture did not initially identify the organism. However, the terminal subculture in a thioglycolate broth grew gram-positive bacilli. The matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) was compatible with Actinomyces oris. After 6 weeks of intravenous ampicillin, the patient remained well with improved cardiac function. We reviewed all reported cases of infective endocarditis caused by Actinomyces species, commenting on clinical characteristics and factors associated with unfavorable outcomes in infective endocarditis due to Actinomyces species. Although infective endocarditis caused by Actinomyces spp is rare, it could be considered in a case of culture-negative endocarditis since the clinical features might be indistinguishable from other bacterial endocarditis. Additionally, MALDI-TOF MS is a useful diagnostic tool for the identification of Actinomyces spp to improve the accuracy of diagnosis.

 

Nehal Mehta Congratulations to Nehal Mehta, MD on being named AFMR's 2020 Outstanding Investigator. Dr. Mehta is being honored for his research demonstrating that treatment with systemic anti-inflammatory medications improves lipid-rich coronary plaque in inflammatory diseases. View a brief video presentation of his work. Dr. Mehta is Section Chief/Inflammation and Cardiometabolic Diseases at the National Heart, Lung and Blood Institute (NHLBI) at the National Institutes of Health (NIH). He is also Professor of Medicine at The George Washington University School of Medicine. Previously, he was Director of Inflammatory Risk at the University of Pennsylvania. More

 

Congratulations to AFMR's 2020 Junior Physician-Investigator Award recipients.

Andrea Hahn, MD
Andrea Hahn, MD
Laneishia K. Tague, MD, MSCI
Laneishia K. Tague, MD, MSCI
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