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Sidharth Mahapatra MD, PhD, Midwestern Section Chair
Sidharth Mahapatra MD, PhD
Midwestern Section Chair
Sidharth Mahapatra MD, PhD

Current Position: Associate Professor of Pediatrics and Biochemistry & Molecular Biology, University of Nebraska Medical Center
Director for Research for the Division of Pediatric Critical Care Medicine

Education: BA Biology, Knox College, Galesburg, IL
MD, PhD, Rosalind Franklin University of Medicine and Science, N. Chicago, IL
Residency & Fellowship, Lucile Packard Children’s Hospital, Stanford, CA

Clinical Interests: Neurocritical care, Pediatric Acute Respiratory Distress Syndrome

Research Interests: Define pathophysiologic events triggering pediatric brain tumors
Generate targeted anti-neoplastic therapeutics against pediatric brain tumors

Awards/Honors:
  • Alpha Omega Alpha (2008)
  • Gold Humanism Honors Society (2009)
  • Leonard P. Tow Humanism in Medicine (2009)
  • Dean's Service Award, Chicago Medical School (2009)
  • Board of Trustees Scholarship Award, Chicago Medical School (2009)
  • Excellence in Teaching, Arnold P. Gold Foundation (2012)
  • Inpatient Fellow of the Year, Lucile Packard Children’s Hospital (2015)
  • Travel Award, Western Society for Clinical Investigation (2015)
  • Young Investigator Coaching Program, Society for Pediatric Research (2017)
  • Top 10 Abstract, American Academy of Pediatrics Society for Critical Care (2017)
  • UNeMED New Innovation Contributor, UNMC (2018)
  • Travel Award, Team Jack Brain Tumor Foundation (2020)
  • K Award, Combined Annual CSCTR and MWAFMR Meeting (2021)

Active Grants

  1. PCCTSDP K12 Scholar Award (K12HD047349)
    01/01/2021 – 12/31/2023
    Project Title: MiR-1253 potentiates cisplatin response in group 3 medulloblastoma through ferroptosis

  2. Team Jack Brain Tumor Foundation Award
    01/01/2020 – 12/30/2022
    Project Title: Chemosensitization of non-SHH/WNT medulloblastoma is regulated by miR-1253

  3. American Cancer Society Institutional Research Grant
    08/01/2020 – 07/31/2021
    Project Title: Exploring the oncogenic properties of NFIB in group 3 medulloblastoma

  4. LB506 (DHHS)
    07/01/2020 – 06/30/2021
    Project Title: Elucidating the oncogenic role of NFIB in group 3 medulloblastoma

  5. LB606 (DHHS)
    07/01/2020 – 06/30/2021
    Project Title: NFIB's role in medulloblastoma stem cell renewal

Current AFMR position: Midwestern Section Chair

Term: 5/01/21 - 04/30/22

As a pediatric intensivist with an interest in neurocritical care working in a state with a punctuated incidence of pediatric brain tumors, I aspire to carve my academic niche studying pediatric medulloblastomas (MB), the most common malignant brain tumor of childhood. Serving as an intersection for my training in molecular neurobiology, my strong interest in translational science, and my burgeoning expertise in pediatric critical care medicine, I hope to significantly impact the long term survivorship of patients with high-risk medulloblastomas, who suffer high relapse rates and mortality.

My secondary clinical interest lies in the study of acute lung injury and pediatric acute respiratory distress syndrome (PARDS). At the institute level, I am studying acute lung injury in the context of bronchiolitis and how critical illness distinguishes this population from their non-critically-ill counterparts. I am also an active member of the Pediatric Acute Lung Injury & Sepsis Investigators (PALISI). We recently participated in a multi-center study on Pediatric Acute Respiratory Distress Incidence and Epidemiology (PARDIE). We are now engaged in the Prone and Oscillator in Pediatrics Clinical Trial (PROSpect) aimed at studying treatment strategies in severe PARDS. Over my career, I aspire to actively engage with collaborators in an effort to mitigate PARDS in the field of critical care.

Sidharth Mahapatra MD, PhD, Councilor-at-Large
Sidharth Mahapatra MD, PhD
Councilor-at-Large
Sidharth Mahapatra MD, PhD

Current Position: Associate Professor of Pediatrics and Biochemistry & Molecular Biology, University of Nebraska Medical Center
Director for Research for the Division of Pediatric Critical Care Medicine

Education: BA Biology, Knox College, Galesburg, IL
MD, PhD, Rosalind Franklin University of Medicine and Science, N. Chicago, IL
Residency & Fellowship, Lucile Packard Children’s Hospital, Stanford, CA

Clinical Interests: Neurocritical care, Pediatric Acute Respiratory Distress Syndrome

Research Interests: Define pathophysiologic events triggering pediatric brain tumors
Generate targeted anti-neoplastic therapeutics against pediatric brain tumors

Awards/Honors:
  • Alpha Omega Alpha (2008)
  • Gold Humanism Honors Society (2009)
  • Leonard P. Tow Humanism in Medicine (2009)
  • Dean's Service Award, Chicago Medical School (2009)
  • Board of Trustees Scholarship Award, Chicago Medical School (2009)
  • Excellence in Teaching, Arnold P. Gold Foundation (2012)
  • Inpatient Fellow of the Year, Lucile Packard Children’s Hospital (2015)
  • Travel Award, Western Society for Clinical Investigation (2015)
  • Young Investigator Coaching Program, Society for Pediatric Research (2017)
  • Top 10 Abstract, American Academy of Pediatrics Society for Critical Care (2017)
  • UNeMED New Innovation Contributor, UNMC (2018)
  • Travel Award, Team Jack Brain Tumor Foundation (2020)
  • K Award, Combined Annual CSCTR and MWAFMR Meeting (2021)

Active Grants

  1. PCCTSDP K12 Scholar Award (K12HD047349)
    01/01/2021 – 12/31/2023
    Project Title: MiR-1253 potentiates cisplatin response in group 3 medulloblastoma through ferroptosis

  2. Team Jack Brain Tumor Foundation Award
    01/01/2020 – 12/30/2022
    Project Title: Chemosensitization of non-SHH/WNT medulloblastoma is regulated by miR-1253

  3. American Cancer Society Institutional Research Grant
    08/01/2020 – 07/31/2021
    Project Title: Exploring the oncogenic properties of NFIB in group 3 medulloblastoma

  4. LB506 (DHHS)
    07/01/2020 – 06/30/2021
    Project Title: Elucidating the oncogenic role of NFIB in group 3 medulloblastoma

  5. LB606 (DHHS)
    07/01/2020 – 06/30/2021
    Project Title: NFIB's role in medulloblastoma stem cell renewal

Current AFMR position: Councilor-at-Large

Term: 05/01/22 - 4/30/25

As a pediatric intensivist with an interest in neurocritical care working in a state with a punctuated incidence of pediatric brain tumors, I aspire to carve my academic niche studying pediatric medulloblastomas (MB), the most common malignant brain tumor of childhood. Serving as an intersection for my training in molecular neurobiology, my strong interest in translational science, and my burgeoning expertise in pediatric critical care medicine, I hope to significantly impact the long term survivorship of patients with high-risk medulloblastomas, who suffer high relapse rates and mortality.

My secondary clinical interest lies in the study of acute lung injury and pediatric acute respiratory distress syndrome (PARDS). At the institute level, I am studying acute lung injury in the context of bronchiolitis and how critical illness distinguishes this population from their non-critically-ill counterparts. I am also an active member of the Pediatric Acute Lung Injury & Sepsis Investigators (PALISI). We recently participated in a multi-center study on Pediatric Acute Respiratory Distress Incidence and Epidemiology (PARDIE). We are now engaged in the Prone and Oscillator in Pediatrics Clinical Trial (PROSpect) aimed at studying treatment strategies in severe PARDS. Over my career, I aspire to actively engage with collaborators in an effort to mitigate PARDS in the field of critical care.

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