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2012 Eastern Regional Meeting April 17-18, 2012 Marriott Wardman Park, Washington, DC
2012 Eastern Regional Meeting
April 17-18, 2012
Marriott Wardman Park Washington, DC

TUESDAY, APRIL 17, 2012
11:00 AM EASTERN MEETING REGISTRATION
12:15 PM - 12:30 PM AFMR INTRODUCTION AND WELCOME
Ravikumar Balasubramanian, MD, PhD
Chair, AFMR Eastern Region
12:30 PM - 1:45 PM SCIENTIFIC SESSION I
Podium Presentations
Moderators: Ofek Hai, MD & Janice P. Dutcher, MD
1. Platelet Granzyme B Induces Contact-Dependent End-Organ Apoptosis During Murine Sepsis
Matthew Sharron1,2, Andrew Wiles1, Claire Hoptay2, Kanneboyina Nagaraju1,2, Robert Freishtat1,2
1Children's National Medical Center, Washington, DC, United States. 2George Washington University School of Medicine, Washington, DC, United States.
2. Low Spinal Bone Mineral Density in Men with Isolated GnRH Deficiency is Related to the Degree of Pubertal Activation of Hypothalamo-pituitary-gonadal Axis.
Edward Horton1, Rohanna Wright2, Flavia Costa Barbosa1, Lacey Plummer1, Jennifer Kaina1, Cassandra Buck1, Ning Jiang1, Richard Quinton2, William F. Crowley Jr.1, Ravikumar Balasubramanian1
1Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA, United States. 2Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
3. Diastolic Function and Survival in Patients with Severe Aortic Stenosis and Normal Left Ventricular Ejection Fraction
Omar K. Khalique1, Robert N. Belkin1, Yat Wa Li1, Wilbert S. Aronow2, Chul Ahn3, Cesare Russo1, Mala Sharma2
1Cardiology, Columbia University Medical Center, New York, NY, United States. 2Cardiology, New York Medical College, Valhalla, NY, United States. 3Clinical Sciences, University of Texas Southwestern, Dallas, TX, United States.
4. Prognostic Value of Cardiac Troponin I in Hospitalized Patients with Pneumonia
Nivas Balasubramaniyam1, Wilbert S. Aronow2, Hoang M. Lai2, Chandrasekar Palaniswamy2, Aileen Lorenzo1, Sahil Khera1, Arun Patil2
1Internal Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, United States. 2Cardiology, Westchester Medical Center/New York Medical College, Valhalla, NY, United States.
5. Functional Gonadotropin-releasing Hormone Deficiency in Men
Hilana Lewkowitz-Shpuntoff 1,2, Ravikumar Balasubramanian1, Niraj Chavan1, Jennifer Kaina1, Andrew Dwyer3, Stephanie Seminara1, Lacey Plummer1, Francis Hayes1, William F. Crowley1, Nelly Pitteloud3
1Massachusetts General Hospital, Boston, MA, United States. 2Albert Einstein College of Medicine, Bronx, NY, United States. 3Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
1:45 PM - 2:00 PM BREAK
2:00 PM - 3:15 PM RESEARCH!AMERICA ADVOCACY WORKSHOP
Suzanne Fflokes
Vice President of Communications
Research!America
View Workshop Description
3:15 PM - 4:15 PM 3rd ANNUAL FORMER AFMR/AFCR PRESIDENT'S ADDRESS
Reflections on a Career in Science and Medicine

William N. Kelley, MD
Professor of Medicine
University of Pennsylvania School of Medicine, Philadelphia, PA
4:15 PM - 6:00 PM POSTER COMPETITION AND RECEPTION
5:00 PM AFMR EASTERN SCHOLARS PRESENTATION
 
WEDNESDAY, APRIL 18, 2012
7:00 AM EASTERN MEETING REGISTRATION
7:30 AM - 8:30 AM BREAKFAST WORKSHOP
Update on Asthma Pathogenesis, Treatment and Airway Remodeling

(Continental Breakfast Will Be Served)

Asthma Pathogenesis, Airway Remodeling and Role of VEGF
Marianne Frieri, MD, PhD
Professor of Medicine & Pathology
SUNY, Stony Brook

Role of Cytokines and TSLP in Asthma Pathogenesis
Larry Borish, MD
Professor of Medicine
University of Virginia

Airway Remodeling, Treatment and Current Perspectives
William W. Busse, MD
Professor of Medicine Allergy, Pulmonary and Critical Care Medicine
University of Wisconsin School of Medicine
8:30 AM - 9:45 AM SCIENTIFIC SESSION II
Podium Presentations
Moderators: Larry Borish, MD & Allison B. Reiss, MD
 
6. Antiphospholipid Antibody Elevation is Associated with "Silent Strokes" in Patients With Patent Foramen Ovale
Ferdinando Buonanno, Ran Meng, Kathleen Feeney, Jing Cao, Eng H. Lo, Mikaela Elia, Molly Thayer, MingMing Ning
Neurology, Mass Gen Hosp/Harvard Med School, Boston, MA, United States.
7. Inhibition of Platelet GPIIb/IIIa Decreases Platelet Aggregation but has No Effect on Granule Release
Claire E. Hoptay, Andrew A. Wiles, Matthew Sharron, Kanneboyina Nagaraju, Robert J. Freishtat
Children's National Medical Center, Washington DC, DC, United States.
8. The Effects of Simvastatin on Human Airway Epithelial Cell Viability and Morphology
Amir A. Zeki1, Saeid Ghavami2, Andrew Halayko2, Reen Wu1
1Pulmonary, Critical Care, & Sleep Medicine, University of California, Davis School of Medicine, Sacramento, CA, United States. 2Section of Respiratory Medicine, University of Manitoba, Winnipeg, MB, Canada.
9. Characterization of a Brugia Malayi–encoded Human IL-5 Receptor Antagonist (BmIL-5Ra) by RNA Interference and Immunofluorescence Microscopy
Rojelio Mejia1, Sara Lustigman3, Ramaswamy Kalyanasundaram2, Thomas B. Nutman1
1NIAID, NIH, Bethesda, MD, United States. 2Department of Biomedical Sciences, University of Illinois, Rockford, IL, United States. 3Lindsay F. Kimball Research Institute, New York, NY, United States.
10. Pediatric Forearm Fractures: Factors Associated With Orthopedic Follow-up After Discharge from the Emergency Department
Nazreen Jamal, Sabah Iqbal, Leticia M. Ryan
Children's National Medical Center, Washington, DC, United States.
9:45 AM - 10:00 AM BREAK
10:00 AM - 11:30 AM INTERACTIVE CAREER DEVELOPMENT WORKSHOP
Creating Mentoring Networks to Optimize Career Development

Ellen W. Seely, MD
GCRC Program Director
Brigham and Women’s Hospital, Boston, MA
11:30 AM - 12:45 PM AFMR PRESIDENTIAL PLENARY (SCIENTIFIC SESSION III)
Podium Presentations
Moderators: Sharma Prabhakar, MD, President & Abraham Thomas, MD, MPH, President-Elect
 
11. Elevated Cerebrospinal Fluid Metalloproteinase-9 is Associated with Poor 6-month Outcome Following Subarachnoid Hemorrhage
Sherry H. Chou1,2,4, Steven K. Feske1,4, Suzanne L. Simmons1, Susannah Orzell1, Rose Du3,4, Andrea Marckmann2, Eng H. Lo2,4, MingMing Ning1,2,4
1Neurology, Brigham and Women's Hospital, Boston, MA, United States. 2Neurology, Massachusetts General Hospital, Boston, MA, United States. 3Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States. 4Harvard Medical School, Boston,MA, United States.
12. Bone Mineral Density and Vitamin D Status in African American Children with Forearm Fractures
Leticia Ryan, Stephen Teach, Cinzia Brandoli, Steven Singer, Rachel Wood, Robert Freishtat, Joseph Wright, Laura Tosi, James Chamberlain
Children's National Medical Center, Washington, DC, United States.
13. Early Disease Characteristics of Enthesitis-related Arthritis Reveals Elevated Transforming Growth Factor-beta
Hemalatha Srinivasalu1,2, Michael G. Barnes3, Gerlinde Layh-Schmitt1, Michael M. Ward1, Robert A. Colbert1
1NIAMS, NIH, Bethesda, MD, United States. 2Pediatric Rheumatology, Nemours/Alfred I duPont Hospital for Children, Wilmington, DE, United States. 3Cincinnati BioBank, Cincinnati Children's Hospital, Cincinnati, OH, United States.
14. Developing a Directional Airway Secretome in Asthmatic Epithelium Using an In Vitro Wound Repair Model
Dinesh Pillai1,2, Binu-John Sankoorikal1,2, Kristy J. Brown1,2, Mary C. Rose1,2, Yetrib Hathout1,2
1Division of Pulmonary and Sleep Medicine, Children's National Medical Center, Washington, DC, United States. 2George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
15. Age at Cancer Diagnosis Depends on Parent of Origin of BRCA Mutation
Simi George, Iuliana Shapira, Daniel Budman, Meredith Akerman, Thomas Bradley, Cinderella Chavez, Christi Hayes, Lora Weiselberg, Vincent Vinciguerra, Sabeen Mekan, Kit Cheng, Sharona Cohen
Hofstra North Shore LIJ School of Medicine, Lake Success, NY, United States.
12:45 PM - 1:00 PM Announcement of Poster Competition Awards
MingMing Ning MD
Chair-Elect, AFMR Eastern Region
1:00 PM Adjourn
 
POSTERS
P1 Prognostic Significance of Frequency and Morphology of Premature Ventricular Complexes During Ambulatory Holter Monitoring
Georges Ephrem1, Michael Levine2, Patricia Friedmann3, Paul Schweitzer2
1Medicine, Beth Israel Medical Center, New York, NY, United States. 2Cardiology, Beth Israel Medical Center, New York, NY, United States. 3Cardiovascular and Thoracic Surgery, Albert Einstein College of Medicine, New York, NY, United States.
P2 Red Blood Cell Distribution Width As a Predictor Of Readmission In Patients With Unstable Angina Or Non ST-Elevation Myocardial Infarction
Georges Ephrem
Medicine, Beth Israel Medical Center, New York, NY, United States.
P3 Inducing Mitotic Dyssynchrony in Normal Airway Epithelium Leads to Production of TGF-ß1
Sarah Alcala1,2, Robert J. Freishtat1
1Children's National Medical Center, Washington, DC, United States. 2The George Washington University, Washington, DC, United States.
P4 Relationship Between Pediatric Early Warning Score and Emergency Department Disposition
Kristen Breslin1, Julie Marx2, Ryan McBeth3, Padmaja Pavuluri4
1. Division of Emergency Medicine, Children's National Medical Center, Washington, DC, United States. 2. Goryeb Children's Hospital, Atlantic Health System, Morristown, NJ, United States. 3. Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY, United States. 4. Division of Pediatric Hospital Medicine, Children's National Medical Center, Washington, DC, United States.
P5 Proteomic Analysis of Bronchial Casts from Patients with Sickle Cell Disease or Congenital Heart Disease
Joi Lucas1, Diego Preciado2, 3, Kristy J. Brown2, 3, Dinesh Pillai1,2, 3, Mary C. Rose2, 3
1. Division of Pulmonary and Sleep Medicine, Children's National Medical Center, Washington, DC, United States. 2. Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, United States. 3. Departments of Integrative Systems Biology, George Washington University, Washington, DC, United States
P6 Analysis and Outcomes of Abnormal ECGs in a Cohort of Patients Seen at an Urban Academic Pediatric Emergency Department
Shilpa Patel1, Elizabeth Anne Greene2, Mohsen Saidinejad1
1. Emergency Medicine, Children's National Medical Center, Washington, DC, United States. 2. Cardiology, Children's National Medical Center, Washington, DC, United States.
P7 Estrogen Inhibits TGFß1-induced Epithelial-Mesenchymal Transition in Asthmatic Airway Cells
Asha S. Payne1,2, 4, Andrew Wiles1, Sarah Alcala5, Kanneboyina Nagaraju1, 3, 4, Robert J. Freishtat1,2, 3
1. Center for Genetic Medicine Research, Children's National Medical Center, Washington , DC, United States. 2. Emergency Medicine and Trauma Center, Children's National Medical Center, Washington , DC, United States. 3. Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC, United States. 4. Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington , DC, United States. 5. Microbiology, Immunology, and Tropical Medicine, George Washington University, Washington , DC, United States.
P8 Achieving Quality Improvement in Patient Care on Labor and Delivery
Diana P. Broomfield, Edom Yared, Nuru Robi, Tiffany Wilson, Long Duc Nguyen
OB/GYN, Howard University Hospital, Washington , DC, United States.
P9 Reproductive Options for HIV Positive Patients in the United States
Lisa J. Green, Tiffany Hailstorks, Diana P. Broomfield
Obstetrics and Gynecology, Howard University Hospital, Washington , MD, United States.
P10 Assessment of Use of Implantable Cardioverter- Defibrillator in African American Patients with Advanced Systolic Heart Failure
Selomie M. Kebede1, Thaslim A. Kassim1, Sirikarn Napan1, Steve Singh2, 1
1. Howard University Hospital, Washington, DC, United States. 2. Veteran Affair Hospital, Washington, DC, United States.
P11 Knowledge of Appropriate Sizing and Defibrillator Pad Position Placement among Emergency Medical Care Providers for Children
Kiesha Fraser, Maybelle Kou, John Howell, Kaidi Fullerton, Charles Sturek
Pediatric Emergency Deparmtment, Inova Health Systems, Falls Church, VA, United States.
P12 Utility of Flexypnea Induction in the Echocardiographic Assessment of Heart Failure
Ofer Sagiv, Michael Vitellas, Gila Perk, Izhak Kronzon
Cardiology, Lenox Hill Hospital, New York, NY, United States.
P13 Relationship Among Fibromyalgia and Rhinitis
Marianne Frieri1, Antigone Argyriou2
1. Medicine, Nassau Univ. Medical Ctr., East Meadow, NY, United States. 2. Physical Medicine & Rehabilitation, Montefiore Medical Center , Bronx, NY, United States.
P14 Unusual Presentation of Facial Angioedema
Marianne Frieri, Reenal Patel
Medicine, Nassau Univ. Medical Ctr., East Meadow, NY, United States.
P15 Erdheim-Chester Disease (ECD): Natural History
Juvianee I. Estrada-Veras, William A. Gahl, Bernadette Gochuico
National Human Genome Research Institutes, National Institutes of Health., Bethesda, MD, United States.
P16 Successful Therapy of Cold Agglutinin Disease Utilizing Rituximab
Michelle Cholankeril, Thomas Bradley, Craig Devoe, Cristina Ghiuzeli, Jonathan Kolitz, Steven Allen
Hematology and Oncology, North Shore University Hospital , Lake Success, NY, United States.
P17 Time-outs Outside of the Operating Room: An Assessment of Time-outs Prior to Bedside Procedures
Kenneth W. McKinley1, Shanu Kurd2, William Schweickert2, Megan Carr-Lettieri2, Marybeth O'Malley2, Shahid Sulaiman2, Jennifer Myers2
1. Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States. 2. Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United States.
P18 The Influence of Race on Mortality and Morbidity following Cardiac Surgery
Joshua Langert1,2, Gregory Trachiotis1,2, Michael Greenberg2, Richard Amdur1,2
1. The George Washington University, Washington, DC, United States. 2. VA Medical Center, Washington, DC, United States.
P19 HIV in the Nation’s Capital: Prevalence of Antiretroviral Resistance in Treatment-Naïve Patients, 2007-2010
Matthew J. Swierzbinski1, Virginia Kan3, David M. Parenti2
1. Internal Medicine, The George Washington University Medical Center, Washington, DC, United States. 2. Infectious Diseases, The George Washington University Medical Center, Washington, DC, United States. 3. Infectious Diseases, Veterans Affairs Medical Center, Washington, DC, United States.
P20 Towards a CTSA-wide Exchange of Experiences and Applets: The RU-BERD Evaluation Tools Suite
Aparna Junuthula, Knut M. Wittkowski
Biostatistics, Epidemiology & Research Design, The Rockefeller University, New York, NY, United States.
P21 From SNPs to Epistatic Regions: Translating GWAS into a Tool for Personalized Medicine
Knut M. Wittkowski1, Martina Durner2, Martin P. Seybold3, Vikas Sonakya1, Hiroshi Mitsui4
1. Biostatistics, Epidemiology & Research Design, The Rockefeller University, New York, NY, United States. 2. Department of Psychiartry, Mount Sinai School of Medicine, New York, NY, United States. 3. Institute for Visualization and Interactive Systems, Stuttgart University, Stuttgart, Germany. 4. Investigative Dermatology, The Rockefeller University, New York, NY, United States.
P22 Postoperative Seizure Outcomes When Interictal Magnetoencephalography Concordant with Ictal Depth Electroencephalography
Kristen Upchurch1, J. Stern2, N. Salamon3, S. Dewar2, D. Eliashiv4, 2
1. University of New Mexico, Albuquerque, NM, United States. 2. Neurology, UCLA, Los Angeles, CA, United States. 3. Radiology, UCLA, Los Angeles, CA, United States. 4. Neurology, Cedars-Sinai, Los Angeles, CA, United States.
P23 Screening for Hepatocellular Carcinoma in Veteran Population has Negligible Impact on Mortality When Cirrhosis Diagnosis and Liver Transplantation Rates Are Low
Alyson McGhan3, David E. Kaplan2, 1
1. GI, University of Pennsylvania, Philadelphia, PA, United States. 2. Philadelphia VAMC, Philadelphia, PA, United States. 3. University of Pennsylvania SOM, Philadelphia, PA, United States.
P24 Renal Cyst Growth in the Post-Nephrectomy Population
Ron Golan, Christina Pasick, Woojin Kim, Parvati Ramchandani
Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, United States.
P25 Etiology of Syncope in Patients Hospitalized With Syncope and Predictors of Mortality and Readmission for Syncope at 17- Month Follow-Up: A Prospective Study
Sahil Khera1, Sachin Sule1, Wilbert S. Aronow1, Chandrasekar Palaniswamy1, Chul Ahn2, Sreedhar Adapa1, Stephen J. Peterson1, Nivas Balasubramaniyam1, Christopher Nabors1
1. Internal Medicine - Cardiology, New York Medical College, Valhalla, NY, United States. 2. Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
P26 The Greater Metropolitan Medical Alumni Council (GMMAC): The Realization of a Need
Elise Belilos1, James M. Oleske2, Norman B. Medow3, Richard Sadovsky4, Christopher L. Campese5, Jacqueline A. Bello3, Kenneth G. Swan2
1. Winthrop University Hospital, Mineola, NY, United States. 2. UMDNJ/New Jersey Medical School, Newark, NJ, United States. 3. Montefiore Medical Center/AECOM, Bronx, NY, United States. 4. SUNY Downstate Medical Center, Brooklyn, NY, United States. 5. North Shore University Hospital, Manhasset, NY, United States.
P27 Prostaglandin (PG)D2 Receptor Ligation Counters Atherogenic Effects of Celecoxib and Restores Cholesterol Efflux Pathways in THP-1 Human Macrophages
Nicholas Famigletti, Iryna Voloshyna, Michael Littlefield, Steven E. Carsons, Allison B. Reiss
Department of Medicine, Winthrop University Hospital, Mineola, NY, United States.
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