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AFMR Foundation

2011 Eastern Regional Meeting April 26-27, 2011 Omni Shoreham Hotel Washington, DC
2011 Eastern Regional Meeting
April 26-27, 2011
Hampton Ballroom
Omni Shoreham Hotel
Washington, DC

TUESDAY, APRIL 26, 2011
11:00 AM EASTERN MEETING REGISTRATION
12:15 PM - 12:30 PM AFMR INTRODUCTION AND WELCOME
Ravikumar Balasubramanian, MD
AFMR Eastern Chair-Elect
12:30 PM - 1:45 PM SCIENTIFIC SESSION I
Podium Presentations
Moderator: Robert Lembo, MD and Leticia Ryan, MD
(Lunch will be provided)
1. Novel Biomarkers of Stroke Progression Identified by Temporal Quantitative Proteomic Screening
MingMing Ning, Mary Lopez, Dave Sarracino, Michael Athenas, David McMullin, Ferdinando S. Buonanno, Eng H. Lo.
Neurology, Mass Gen Hosp/Harvard Med School, Boston, MA, United States
2. Speckle Tracking-Derived Diastolic Function Predicts Mortality in Patients with Acute Coronary Syndrome.
Sirikarn Napan, Thaslim Kassim, Bryan Curry, Michael Greenberg
Howard University, Washington, DC, United States
3. The Effect of Race on All-cause Mortality After Cardiac Surgery. A Single Institutional Experience in a Veteran Population Over 20 years
Isaac Opoku-Asare1, Thaslim Kassim4, Rebecca Chornock3, Jason Morrissette3, Erin Goheen3, Peter Kokkinos3, Micheal D. Greenberg1,3, Gregory Trachiotis2
1Cardiovascular Medicine, Howard University Hospital, Washington, DC, United States. 2Cardiothoracic Surgery, Veteran Medical Center, Washington, DC, United States. 3Cardiology, Veteran Medical Center, Washington, DC, United States. 4Internal Medicine, Howard University Hospital, Washington, DC, United States.
4. Olfactory Phenotyping in Isolated Gonadotropin Releasing Hormone Deficiency: A Systematic Analysis
Hilana M. Lewkowitz-Shpuntoff, Ravikumar Balasubramanian, Virginia Hughes, Margaret Au, William F. Crowley
Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA, United States
5. Outcomes and Survival with Aortic Valve Replacement Compared with Medical Therapy in Patients with Low-, Moderate-, and Severe-gradient Severe Aortic Stenosis and Normal Left Ventricular Ejection Fraction
Mala Sharma1, Omar Khalique1, Wilbert S. Aronow1, Robert N. Belkin1, Chul Ahn2
1Cardiology, Westchester Medical Center of New York Medical College, Valhalla, NY, United States. 2University of Texas Southwestern Medical Center, Dallas, TX, United States.
1:45 PM - 2:00 PM BREAK
2:00 PM - 3:15 PM RESEARCH!AMERICA ADVOCACY WORKSHOP
Mary Wooley
President and CEO
Research! America

The US sets the world standard for research, yet very few Americans know much about research, research institutions or researchers. Not many Americans can name a living researcher or any institution where research is conducted. Is it then any wonder that public policy-makers often overlook or underrate the value of supporting science or agencies like the NIH? World-class science cannot be long sustained without science leaders who speak effectively about the value of science, answering questions and always keeping a finger on the pulse of public sentiment. Re-directing communication styles appropriate to the academic realm to that of media, the public and elected officials is essential if science leaders want to get our message across. Public opinion data is a powerful resource to track public perceptions of science and to help shape messages that are “in the moment.” Adopting a habit of mind and practice that crafts messages linking the value of research to current public concerns is actually straightforward: today, for example, it means linking research to its economic impact, job creation, and critical role in maintaining U.S. competiveness, as well as to achieving better health. Whether for lack of recognition of the problem, lack of training, lack of reinforcement or all three, scientists rarely master the tools of advocacy. Effective leadership for science requires strong communication skills, setting the stage for delivery of a unified message to the public and decision-makers. By becoming stronger communicators and embracing their role as advocates, AFMR members can better garner and maintain public support for the life-saving work they undertake every day in the public’s interest.
3:15 PM - 4:15 PM 2nd ANNUAL FORMER AFMR/AFCR PRESIDENT'S ADDRESS
30 Years of HIV/AIDS: A Personal Journey

Anthony S. Fauci, MD
Director, National Institute of Allergy and Infectious Diseases (NIAID)
Chief, NIAID Laboratory of Immunoregulation
National Institutes of Health (NIH)
AFMR/AFCR President 1980-1981

Dr. Fauci has been involved in the fight against HIV/AIDS since AIDS first was described in 1981. During his lecture, he will provide a personal perspective on the events related to HIV/AIDS over thirty years, from his vantage point as a physician-scientist and research administrator who has interacted with each U.S. President in the AIDS era, from Ronald Reagan to Barack Obama. Among many issues, he will discuss the dramatic evolution of therapy for HIV-infected individuals, the role of activism in HIV/AIDS science, the development of the President’s Emergency Plan for AIDS Relief (PEPFAR), and exciting new developments in HIV prevention.
4:15 PM - 6:00 PM POSTER COMPETITION AND RECEPTION
5:30 PM - 6:00 PM AFMR EASTERN SCHOLARS PRESENTATION
 
WEDNESDAY, APRIL 27, 2011
7:00 AM EASTERN MEETING REGISTRATION
7:30 AM - 8:30 AM BREAKFAST WORKSHOP:

CARDIOVASCULAR RISK IN AUTOIMMUNE RHEUMATIC DISORDERS
(Continental Breakfast Will Be Served)
Moderator: Marianne Frieri, MD, PhD

Cardiovascular Risk in SLE
Marianne Frieri, MD, PhD

Atherogenic Impact of Rheumatoid Arthritis: Disruption of Cholesterol Metabolism and Transport
Allison Reiss, MD

Atherosclerosis in Lupus: Ongoing Studies in Prevention and Treatment
Michelle Petri, MD, MPH
8:30 AM - 9:45 AM SCIENTIFIC SESSION II
Podium Presentations
Moderators: Peter H. Wiernik, MD & Rojelio Mejia, MD
6. Renal Cell Carcinoma and Hematologic Malignancy in the Same Patients
Janice P. Dutcher, Peter H. Wiernik
Medicine, St Lukes-Roosevelt Hospital Center, New York, NY, United States.
7. The Role of C-Arm Computed Tomography In The Treatment Of Venous Malformations And Prediction Of Local Skin Complications
Deddeh Ballah, Xiaowei Zhu, J. Christopher Edgar, Anne Marie Cahill
Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
8. Sepsis-related Mortality is Reduced in the Absence of Granzyme B
Claire E. Hoptay1,2, Andrew A. Wiles1, Matthew Sharron1,2, Mayya Geha2, Kanneboyina Nagaraju1,2, Robert J. Freishtat1,2
1Children's National Medical Center, Washington DC, United States. 2George Washington University, Washington, DC, United States.
9. Stress Induced Left Ventricular Ejection Fraction Augmentation During Gated Single Photon Emission Computed Tomography Myocardial Perfusion Imaging Has No Survival Advantage.
Selasie Samuel Mortoti1, Isaac Opoku-Asare1, Thaslim Kassim1, Peter Kokkinos2, Erin Goheen2, Gregory Trachiotis2, Rebecca Churn2, Michael Greenberg2,1
1Medicine/Cardiology, Howard University Hospital, Washington, DC, United States. 2Medicine/Cardiology, Veteran Affairs Medical Center, Washington, DC, United States.
10. Beneficial Glucocorticoid Effects In Asthmatic Airway Epithelium Are Not Dependent On Receptor- Mediated Transcription
Robert J. Freishtat1, Jesse Damsker2, Angela S. Benton1, Alan M. Watson1, Erica Reeves2, Mary C. Rose1, Kanneboyina Nagaraju1,2, Eric P. Hoffman1, 2
1Children's National Medical Center, Washington, DC, United States. 2Validus Biopharma, Inc., Rockville, MD, United States.
9:45 AM - 10:00 AM BREAK
10:00 AM - 11:00 AM CAREER DEVELOPMENT WORKSHOP
David Armstrong, PhD
Chief, Scientific Review Branch
National Institute of Mental Health, National Institutes of Health

Eric Brown, PhD
Scientific Review Administrator
Review Branch
National Institute of Arthritis and Musculoskeletal and Skin Diseases

Dr. David Armstrong and Dr. Eric Brown are experts of NIH grant processes for many years and maintain an excellent understanding of the complex guidelines involved with grant application and review. During the Career Development Workshop, Drs. Armstrong and Brown will evaluate the NIH grant review process from the NIH Scientific Review perspective, provide the audience with valuable information about the new guidelines for application and peer review process, and answer questions from attendees.
11:00 AM - 12:15 PM AFMR PRESIDENTIAL PLENARY (SCIENTIFIC SESSION III)
Podium Presentations
Moderators: Francis Miller, MD, President and Sharma Prabhakar, MD, President-Elect
11. Oxygen Tension Affects Release of Adenosine from Astrocytes
Tobias B. Kulik1, H Richard Winn2
1Neurology, University of Rochester, Rochester, NY, United States. 2Neurosurgery, Mount Sinai School of Medicine, New York, NY, United States.
12. FGF-2: A novel Urinary Biomarker for Acute Kidney Injury in Children with Critical Illnesses
Kitman Wai1, Sofia Perazzo2, Angel Soler-Garcia2, Patricio E. Ray2
1Critical Care, Children's National Medical Center, Washington, DC, United States. 2Children's Research Institute, Children's National Medical Center, Washington, DC, United States.
13. Expression of the Lectin Like Oxidized Low-density Lipoprotein Receptor-1 (LOX-1) in Endothelial Cells Mediated by Adenosine A2A Receptor.
Miguel Lorenz, Iryna Voloshyna, Michael Littlefield, Allison B. Reiss
Internal Medicine, Winthrop University Hospital, Mineola, NY, United States.
14. Platelet-Induced Splenocyte Apoptosis during Sepsis is Inhibited by GPIIb/IIIa Blockade
Matthew Sharron1,2, Andrew A. Wiles1, Claire Hoptay1,2, Mayya Geha1, Angela S. Benton1,2, Kanneboyina Nagaraju1,2, Robert J. Freishtat1,2
1Children's National Medical Center, Washington, DC, United States. 2George Washington University School of Medicine, Washington, DC, United States.
15. Atherogenic Properties of Coxibs in Human Monocytes/Macrophages
Scherly Leon1,2, Iryna Voloshyna1, Michael Littlefield1, Allison B. Reiss1
1Medicine, Winthrop University Hospital, Mineola, NY, United States. 2Medicine, New York Hospital of Queens, Flushing, NY, United States.
12:15 PM - 12:30 PM Announcement of Poster Competition Awards
12:30 PM Adjourn
 
POSTERS
P1 A Novel Method to Predict Increased Left Ventricular Mass Index
Angelica J. Motta1,2, Victor Sein1, Richard Gerkin1,2, Akil Loli1, Kenneth Desser1
1Cardiology, Banner Good Samaritan Medical Center, Phoenix, AZ, United States. 2Internal Medicine, Banner Good Samaritan Medical Center, Phoenix, AZ, United States.
P2 Digital Thermal Monitoring and Outcomes in Nuclear Stress Testing
Samantha Jagger, Harvey Hecht, Georgia Panagopolos, Vivek Kumar, Neil L. Coplan
Cardiovascular Medicine, Lenox Hill Hospital, New York, NY, United States.
P3 Comparisons of Speckle Tracking Echocardiography, Tissue Doppler Imaging and Transmitral Flow Velocity for Estimation of Diastolic Function in Petients with Acute Coronary Syndrome
Thaslim Ahamed Kassim, Sirikarn Napan, Michael Greenberg, Bryan Curry
Howard University Hospital, Washington DC, United States.
P4 Low Usage of Hydralazine and Isosorbide Dinitrate Therapy in Eligible Heart Failure Patients During Hospitalization or at Discharge
Isaac Opoku-Asare1, Thaslim A. Kassim2, Sirikan Napan1, Steve Singh3
1Cardiology, Howard University Hospital, Washington , DC, United States. 2Internal Medicine, Howard University Hospital, Washington, DC, United States. 3Cardiology, Veterans Medical Center, Washington, DC, United States.
P5 Paradoxical Embolus Across a Patent Foramen Ovale as a Possible Etiology of Acute ST Elevation Myocardial Infarction
Peter Hynes, James Coromilas
Department of Medicine, Division of Cardiovascular Diseases and Hypertension, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
P6 Left Bundle Brach Block Should Not Be Used As An ST Segment Elevation Equivalent In The Management Of Acute ST Elevation Myocardial Infarction
Michelle D. Spotnitz, Michael Cargill, Kathryne Cappucci, James Coromilas
Medicine, Division of Cardiology, UMDNJ-Robert Wood Johnson, New Brunswick, NJ, United States.
P7 Mechanisms Involved in the Reduction of Ventricular Arrhythmias by Angiotensin II Converting Enzyme Inhibitors and Possible Role of Angiotensin II Receptor Blockers
Pablo I. Altieri, Hector L. Banchs, Nelson Escobales, Maria Crespo
Medicine and Physiology Department, University of Puerto Rico, San Juan, Puerto Rico.
P8 Long Term Results of Isolated Valve Operations In Patients With Diabetes.
Afamefuna Onuora1,2, Gregory Trachiotis2, Philip S. Mullenix2, Isaac Opoku-Asare1,2, Erin Goheen2, Michael D. Greenberg1,2
1Cardiology, Howard University Hospital, Washington DC, United States. 2Cardiology, Veterans Affairs Medical Center, Washington DC, United States.
P9 Have Accreditation Council for Graduate Medical Education Duty Hour Limits Made a Difference? A Re-examination of Resident Sleep, Mental Health, Education, and Safety Seven Years Later
Hanna Kim1,2, Bernhard Wiedermann1,2
1Children's National Medical Center, Washington, DC, United States. 2George Washington University, Washington, DC, United States.
P10 Resident Education in an Early Head Start (EHS) Program: A New Model to Enhance Medical Education and Community Involvement
Victoria Chen, Daniel DeSalvo, Hari Tunuguntla, Cara Lichtenstein
Children's National Medical Center, Washington, DC, United States.
P11 Home Fire Safety Practices in an Urban Pediatric Emergency Department Population
Rachel Wood1, Alexandra Rucker1, Ambika Lall2, Stephen Teach1, Joseph Wright1, James Chamberlain1, Leticia Ryan1
1Children's National Medical Center, Washington, DC, United States. 2Howard University College of Medicine, Washington, DC, United States.
P12 Implementation and Impact of a Consensus Diagnostic and Management Algorithm for Complicated Pneumonia in Children
Dinesh Pillai1, Xaioyang Song2, William Pastor3, Mary Ottolini4, David Powell5, Bernhard L. Wiedermann2, Roberta L. DeBiasi2
1Division of Pulmonary Medicine, Children's National Medical Center, Washington, DC, United States. 2Division of Infectious Diseases, Childrens National Medical Center, Washington, DC, United States. 3Quality Improvement & Clinical Support Services, Childrens National Medical Center, Washington, DC, United States. 4Division of Hospitalist Medicine, Childrens National Medical Center, Washington, DC, United States. 5Division of Pediatric Surgery, Childrens National Medical Center, Washington, DC, United States.
P13 Recognizing Opioid and Benzodiazepine Related Adverse Drug Events in Children Through an Automated Detection System
Kitman Wai, Brian Jacobs, David Stockwell
Critical Care, Children's National Medical Center, Washington, DC, United States.
P14 WITHDRAWN
P15 Comparison of Hemolysis Between the Centrifugal and Roller-Head Pumps During ECMO at Low Flow Rates
Sonali Basu1, Pamela Garcia-Filion2, Heidi Dalton2
1Critical Care Medicine, Children's National Medical Center, Washington, DC, United States. 2Critical Care Medicine, Phoenix Children's Hospital, Phoenix, AZ, United States.
P16 WITHDRAWN
P17 Familial Polycythemia Vera in a patient with Iron Deficiency Anemia
Nneamaka Enwemnwa1, Nidhi Mishra1, Christ-moi Cheres1, Abhinav Chandra2, Thandavababu Chelliah1
1Medicine, Coney Island Hospital, Brooklyn, NY, United States. 2Hematology /Oncology, Maimonides Medical Center, Brooklyn, NY, United States.
P18 A Rare Initial Presentation of Uncommon Disorder
Pavankumar B. Patel, Molly Trostle, Mariya Apostolova, Kim Al Soudi
Internal Medicine, Memorial Medical Center, Johnstown, PA, United States.
P19 Characteristics of Necrolytic Acral Erythema in Patients with Chronic Hepatitis C Virus
Zachariah Dorey-Stein1, Brian A. Raphael2, Vincent Lo Re1, Carrie Kovarik2
1Clinical Center for Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, United States. 2Dermatology, University of Pennsylvania, Philadelphia, PA, United States.
P20 The Use of Sedatives Drugs Among the In-Hospital Elderly Patients, Indications and Complications
Valeriya Vaynshteyn, Anita Kumari, Suriya Jayawardena, Donna Seminara
Geriatrics, Staten Island University Hospital, Staten Island, NY, United States.
P21 Etiologies and Risk Factors For Rehospitalization For Syncope And For Long-Term Mortality In 325 Consecutive Patients Hospitalized For Syncope.
Sreedhar R. Adapa, Sachin Sule, Chandrasekar Palaniswamy, Wilbert Aronow, Stephen Peterson, Lakshmi Mudambi
Department of Medicine, New York Medical College, Valhalla, NY, United States.
P22. Synchronizing Mitosis Reduces Intrinsic Inflammation in Asthmatic Airway Epithelium
Angela S. Benton1, Alan M. Watson1, Jesse Damsker2, Erica Reeves2, Mary C. Rose1, Eric P. Hoffman1,2, Robert J. Freishtat1
1Children's National Medical Center, Washington, DC, United States. 2Validus Biopharma, Rockville, MD, United States.
P23 Using Quantity of Pubic Gray Hairs as a Predictor of Dimished Ovarian Reserve
Diana P. Broomfield1, James Rodriguez II2, Etka Vishwakarma1
1OB/GYN, Howard University Hospital, Washington, DC, United States; 2Oakwood University, Huntsville, AL, United States.
P24 Predictors of Forearm Frature Risk in African American Children
Leticia Ryan, Stephen Teach, Cinzia Brandoli, Steven Singer, Rachel Wood, Robert Freishtat, Joseph Wright, Laura Tosi, James Chamberlain
Children's National Medical Center, Washington, DC, United States.
P25 Factors Associated with Orthopedic Intervention for Pediatric Forearm Fractures
Leticia Ryan1, Stephen Teach1, Uchenna Ezeibe2, Ambika Lall2, Rachel Wood1, Joseph Wright1, James Chamberlain1
1Children's National Medical Center, Washington, DC, United States. 2Howard University College of Medicine, Washington, DC, United States.
P26 Lateral Medullary Infarct Presenting as Vomiting and Vertigo
Katharine L. Modisett, David R. Lane
Emergency Medicine, Georgetown University School of Medicine, Washington, DC, United States.
P27 Effect of Cardiac PFO Physiology on Circulatory Proteomic Profile in Stroke Patients
MingMing Ning, Ferdinando S. Buonanno, Michael Athenas, Dave Sarracino, Bryan Krastins, Zareh Demirjian, Ignacio Inglessis, David McMullin, G William Dec, Igor Palacios, Mary Lopez, Eng H. Lo
Mass Gen Hosp/Harvard Med School, Boston, MA, United States.
P28 Neurotoxicity of Chlorinated Dopamine.
Shadab Kalim1, Irving Gomolin1, Ahmed Ibrahim1, Thomas Palaia1, Louis Ragolia1, E. J. Delikatny2, Thomas M. Jeitner1
1Winthrop University Hospital, East Meadow, NY, United States. 2University of Pennsylvania, Philadelphia, PA, United States.
P29 Placental Hypervascularity Does Not Cause Perinatal Brain Injury
Radford Shanklin2,1, Mohammad Amiri1
1Pathology-Laboratory Medicine, University of Tennessee, Memphis, TN, United States. 2Marine Biological Laboratory, Woods Hole, MA, United States.
P30 Osteopontin is Significant in Pediatric Asthma
Asha S. Payne1,2, Sree Rayavarapu1,2, Angela Benton1,2, Robert J. Freishtat1,2, Sabah Iqbal1,2
1Children's National Medical Center, Washington, DC, United States. 2George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
P31 Asthmatic Airway Epithelial Secretions Reduce Normal Airway Epithelial Mitotic Regeneration
Suraiya Kureshi1, Benton S. Angela3, Alan M. Watson3, Amber Lee3, Mary C. Rose3, Robert J. Freishtat2,3
1Pediatric Pulmonary Department, Children's National Medical Center, Washington, DC, United States. 2Pediatric Emergency Medicine, Children's National Medical Center, Washington, DC, United States. 3Integrative Systems Biology, Children's National Medical Center, Washington, DC, United States.
P32 Respiratory Infections and Vitamin D
Sabah F. Iqbal1,2,3, Edward V. Mosenkis2, Pankaj Jain2, Andrew Wiles2, Jennifer Lerner2, Angela S. Benton2, James M. Chamberlain1, Robert J. Freishtat1,2,3, Stephen J. Teach1
1Division of Emergency Medicine, Children's National Medical Center, Washington, DC, United States. 2Center for Genetic Medicine, Children's National Medical Center, Washington, DC, United States. 3Department of Integrative Systems Biology, George Washington University School of Medicine, Washington, DC, United States.
P33 Mold and Asthma in an Urban Inner-City Pediatric Population
Sabah F. Iqbal1,2,3, Jennifer Lerner2, Andrew Wiles2, Angela S. Benton2, James M. Chamberlain1, Robert J. Freishtat1,2,3
1Division of Emergency Medicine, Children's National Medical Center, Washington, DC, United States. 2Center for Genetic Medicine, Children's National Medical Center, Washington, DC, United States. 3Department of Integrative Systems Biology, George Washington University School of Medicine, Washington, DC, United States.
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