American Federation for Medical Research
2018 Final Program

Friday, March 16, 2018
6:30 AM - 7:30 AM
EASTERN MEETING REGISTRATION & CONTINENTAL BREAKFAST
7:00 AM - 8:15 AM
BREAKFAST SYMPOSIUM
Lipid Metabolism and Treatment: New Insights from Childhood to Adulthood
Moderators: Shireen Atabaki, MD, Children's National Medical Center, Washington DC
Oana Sandu, MD, Albert Einstein College of Medicine, Bronx, NY

Speakers:
Management of Hyperlipidemia: A Pediatric Dilemma
Siham Accacha, MD, NYU Winthrop Hospital, Mineola NY
Diagnosis and Treatment of Heterozygous Familial Hypercholesterolemia in the Era of PCSK9 Inhibitors
Cindy Bredefeld, DO, FACE, NYU Winthrop Hospital, Mineola NY
Statin Safety, Intolerance and the Nocebo Effect
Connie B. Newman, MD, NYU Langone Medical Center, New York NY

8:15 AM – 8:30 AM
AFMR INTRODUCTION AND WELCOME
Allison B. Reiss, MD, NYU Winthrop Hospital, Mineola NY
Chair, AFMR Eastern Section Council
8:30 AM - 10:30 AM
AFMR PRESIDENTIAL PLENARY SESSION (SCIENTIFIC SESSION I):
Cardiovascular Disease & Pulmonology
Moderators: MingMing Ning, MD, MMSc. Mass General Hospital/Harvard Medical School, Boston, MA
Yutong Zhao, MD, PhD, University of Pittsburgh, Pittsburgh, PA
1.
A Phase IV, Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effects of Ustekinumab on Vascular Inflammation in Psoriasis (The Vip-U Trial).
Joel M. Gelfand2, Junko Takeshita2, Amit Dey1, Daniel Shin2, Megan Noe2, Zelma Chiesa Fuxench2, Aditya A. Joshi1, Judith Alvarez2, Suzette Baez Vanderbeek2, Charlotte L. Harrington1, Tom Werner2, Martin P. Playford1, Drew Torigian2, Mark A. Ahlman1, Abass Alavi2, Nehal N. Mehta1
1Cardiology, NHLBI, NIH, Bethesda, Maryland, United States, 2University of Pennsylvania, Philadelphia, Pennsylvania, United States
2.
Evaluation of Biologic Therapy versus Triple DMARD Therapy in RA Patients Unresponsive To Methotrexate
Nicholas A. Vernice, Allison B. Reiss, Heather A. Renna, Joshua DeLeon, Steven Carsons, Lora J. Kasselman
Biomedical Research, NYU Winthrop Hospital, Mineola, New York, United States
3.
A Small Peptide Blocking Inhibitor Diminishes Inflammatory Responses though Promoting Lysophosphatidic Acid Receptor 1 Degradation
Shuang Li1,2, Jianxin Wei2, Su Dong2, Jing Zhao2, Dong Shang1, Yutong Zhao2
1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania, United States
4.
GlycA, a Novel Inflammatory Biomarker, IS Inversely Associated with Aortic Distensibility in Patients with Psoriasis
Leonard D. Genovese1, Aditya A. Joshi1, Martin P. Playford1, Parag Shukla1, Amit Dey1, Jacob W. Groenendyk1, Youssef A. Elnabawi1, Agastya D. Belur1, Aditya Goyal1, Navya Nanda1, Mark A. Ahlman1, Heather L. Teague1, Yvonne Baumer1, Joel M. Gelfand2, Alan T. Remaley3, Nehal N. Mehta1
1NHLBI, National Institute of Health, Washington, District of Columbia, United States, 2Dermatology, UPenn, Philadelphia, Pennsylvania, United States, 3NIH, Bethesda, Maryland, United States
5.
Aortic Wall Thickness by MRI IS Directly Related to Non-Calcified Coronary Plaque Burden by Quantitative Coronary CT Angiography in Patients with Psoriasis
Youssef A. Elnabawi, Jacob W. Groenendyk, Amit Dey, Aditya Goyal, Agastya D. Belur, Jonathan Chung, Parag Shukla, Mark A. Ahlman, Aditya A. Joshi, Martin P. Playford, Marcus Y. Chen, Nehal N. Mehta
NHLBI, National Instititues of Health, Bethesda, Maryland, United States
6.
Amygdala Activity Assessed by 18-FDG PET/CT Is Associated with Non-Calcified Coronary Plaque Burden Quantified by Coronary Computed Tomography Angiography in Psoriasis
Aditya Goyal, Tsion Aberra, Youssef A. Elnabawi, Amit Dey, Jonathan Chung, Agastya D. Belur, Jacob W. Groenendyk, Abhishek Chaturvedi, Joseph Lerman, Joshua Rivers, Charlotte L. Harrington, Nevin Varghese, Gregory Sanda, Heather L. Teague, Yvonne Baumer, Justin Rodante, Mark A. Ahlman, David Bluemke, Martin P. Playford, Marcus Y. Chen, Aditya A. Joshi, Nehal N. Mehta
Cardiometabolic Diseases, National Heart, Lung & Blood Institute, Bethesda, Maryland, United States
7.
Redefining Bronchiolitis: Respiratory Phenotyping of Viral Lower Respiratory Tract Infections Identifies Subsets with Distinct Acute Severity and Recurrence of Respiratory Illnesses in Young Children
Maria A. Arroyo Morr1, Kyle Salka1, Geovanny Perez1, James Jackson1, Dinesh Pillai1, Carlos Rodriguez Martinez2, Gustavo Nino1
1Pulmonary, Children's National Health System, Washington , District of Columbia, United States, 2Neumologia, Bogota, Colombia
8.
Interleukin-1 Beta Is Associated with Aortic Vascular Inflammation Assessed by 18-FDG PET/CT in Patients with Psoriasis
Agastya D. Belur1, Youssef A. Elnabawi1, Amit Dey1, Aparna A. Sajja1, Aditya Goyal1, Charlotte L. Harrington1, Jacob W. Groenendyk1, Heather L. Teague1, Yvonne Baumer1, Navya Nanda1, Mark A. Ahlman2, Aditya A. Joshi1, Martin P. Playford1, Nehal N. Mehta1
1NHLBI, National Institutes of Health, Bethesda, Maryland, United States, 2National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, United States
9.
Improvement in Large Density HDL Particle Number by NMR IS Associated with Improvement in Vascular Inflammation by 18-FDG PET/CT at One-year in Psoriasis
Amit Dey1, Martin P. Playford1, Aditya A. Joshi1, Agastya D. Belur1, Aditya Goyal1, Youssef A. Elnabawi1, Jacob W. Groenendyk1, Jonathan Chung1, Joshua Rivers1, Justin Rodante1, Leonard D. Genovese1, Aparna A. Sajja1, Charlotte L. Harrington1, Nevin Varghese1, Parag Shukla1, Tsion Aberra1, Heather L. Teague1, Yvonne Baumer1, Alan T. Remaley1, Mark A. Ahlman1, Joel M. Gelfand2, Nehal N. Mehta1
1Cardiology, NHLBI, NIH, Bethesda, Maryland, United States, 2University of Pennsylvania, Philadelphia, Pennsylvania, United States
10.
Inhibition of the SCFFBXO3 E3 Ligase as a Novel Anti-Inflammatory Therapy for Atherosclerosis
Divay Chandra, James Londino, Bill Chen, Rama Mallampalli
Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States
11.
Improvement in Skin Disease Severity is Associated with Reduced Progression of Aortic Wall Thickness in Patients with Psoriasis
Jacob W. Groenendyk, Parag Shukla, Agastya D. Belur, Amit Dey, Youssef A. Elnabawi, Justin Rodante, Aditya Goyal, Ahmed Sadek, Navya Nanda, Mark A. Ahlman, Aditya A. Joshi, Martin P. Playford, Nehal N. Mehta
NHLBI, National Institutes of Health, Bethesda, Maryland, United States
12.
Atherosclerosis in Autoimmune Rheumatic Diseases: Comparison of Plasma Effects on Macrophage Cholesterol Balance in vitro, and Correlation to Traditional Cardiovascular Disease Clinical Risk Factors
Andrew Maidhof1, Lora J. Kasselman2, Steven Carsons1,2, Elise Belilos1, Kristina Belostocki1, Gary Rosenblum1, Lois Bonetti1, Melissa Fazzari2, Joshua DeLeon1, Allison B. Reiss1,2
1Medicine, NYU Winthrop Hospital, Mineola, New York, United States, 2Winthrop Research Institute, NYU Winthrop Hospital, Mineola, New York, United States
10:30 AM - 10:45 AM
BREAK
10:45 AM - 11:30 AM
9TH ANNUAL FORMER AFMR/AFCR PRESIDENT'S ADDRESS
J. Sanford Schwartz, MD, University of Pennsylvania, Wharton School, Philadelphia PA
Professor of Medicine, Health Care Management and Economics
11:30 AM - 12:45 PM
MODERATED POSTER LUNCH COMPETITION
Moderators: Elvira Gosmanova, MD, FASN Samuel S. Stratton VA Medical Center, Albany NY
Wojciech Blogowski, MD, PhD, University of Zielona Gora, Poland
MP1.
Pulmonary and Abdominal Tuberculosis
Theo D. Trandafirescu
Medicine, Mount Sinai Services, Queens Hospital Center, Flushing, New York, United States
MP2.
Lipoprotein Cholesterol Changes across Increasing Stages of Type 2 Diabetes Mellitus
Bin Gui1, Evan Siau2, Louis F. Amorosa1
1Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States, 2Medicine, St. Barnabas Hospital, New York City, New York, United States
MP3.
Burden of Gene Mutations in Caribbean Women with Breast Cancer
Edwin Chiu1, Bachar Samra1, Gordon Moffat2, Eduardo Hernandez2, Iuliana Shapira1
1Department Hematology/Oncology, SUNY Downstate Medical Center, Brooklyn, New York, United States, 2Department Internal Medicine, SUNY Downstate Medical Center, Brooklyn, New York, United States
MP4.
Dual versus Single Anti-Platelet Therapy after Trans Catheter Aortic Valve Replacement
Sunny Goel, Hitesh Raheja, Jacob Shani
Cardiology, Maimonides Medical Center, Brooklyn, New York, United States
MP5.
Acute Phase Ketosis-Prone Atypical Diabetes Is Associated with a Pro-Inflammatory Profile: A Case-Control Study in a Sub-Saharan African Population
Eric Lontchi-Yimagou1, Philippe Boudou2, Jean Louis Nguewa2, Jean Claude Mbanya3, Jean-Francois Gautier2, Eugene Sobngwi3
1Medicine, Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York, Bronx, New York, United States, 2INSERM, UMRS 1138, Centre de Recherche des Cordeliers, Paris, France, 3National Obesity Centre, Yaoundé Central Hospital, Yaoundé, Cameroon
MP6.
Takotsubo Cardiomyopathy: A Systematic Review of the Literature
Nicole Pristera1, Zainab Samad2
1Internal Medicine, Duke University Hospital, Durham, North Carolina, United States, 2Cardiology, Duke University Hospital, Durham, North Carolina, United States
MP7.
Barriers to Hepatitis C Treatment - Internal Medicine Resident’s Perspectives in a Community Care Setting
Mazin O. Khalid1, Sumit Dahal1, Vijay Gayam1, Amrendra Mandal1, Mowyad Khalid2, Muhammad Rajib HOSSAIN1, Osama Mukhtar1
1Medicine, Interfaith Medical Center, Brooklyn, New York, United States, 2Medicine, Wayne state university, Detroit, Michigan, United States
MP8.
Healthcare Disparities in Genetic Testing for Hereditary Cancers in the African American Population
Bachar Samra1, Edwin Chiu1, Iuliana Shapira2
1Hematology/Oncology, SUNY Downstate Medical Center, Brooklyn, New York, United States, 2Hematology Oncology, SUNY Downstate Medical Center, Brooklyn, New York, United States
MP9.
Intrinsic Inflammatory and Innate Immune Gene Profiling in Pediatric Asthmatic Airway Epithelium
Samira Naime, James Jackson, Geovanny Perez, Gustavo Nino, Dinesh Pillai
Children's National Medical Center, Washington, District of Columbia, United States
MP10.
Chronic Hepatitis C Genotype 4 Infection Treatment Response in Community Care Setting
Vijay Gayam, Mazin Khalid, Muhammad Rajib HOSSAIN, Pavani Garlapati, Arshpal Gill, Osama Mukhtar
Medicine, Interfaith Medical Center, Brooklyn, New York, United States
12:45 PM - 2:45 PM
SCIENTIFIC SESSION II: Hematology, Oncology, Neuroscience & Gastroenterology/Hepatology
Moderators:
Janice Dutcher, MD, Cancer Research Foundation, Bronx NY
Peter Wiernik, Cancer Research Foundation, Bronx NY
13.
The Mechanism of Homologous Recombinations' Upregulation in the p53/p21Waf1-compromised Cells: Implications for Drug Resistance to Camptothecin
Larisa Y. Romanova1,2, J. F. Mushinski1, A.L. Kovalchuk2
1Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, United States, 2Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, United States
14.
Management of Refractory Anti-Phospholipid Syndrome
Babak Baseri1, Alina Bhat1, Bachar Samra1, Jason Gonsky1,2
1Department of Hematology and Oncology, SUNY Downstate Medical Center, Brooklyn, New York, United States, 2Department of Hematology and Oncology, Kings County Hospital, Brooklyn, New York, United States
15.
Differential Circulating MicroRNA Expression in Healthy Black and White Women May Account for Differential Cancer Incidence and Outcomes
Iuliana Shapira1, Paul Abrudescu1, Erica Testani1, Ameer Aboud1, Annette Lee2
1Medicine, SUNY Downstate, Brooklyn, New York, United States, 2Genomic and Genetic, Feinstein Institute for Medical Research, Manhasset, New York, United States
16.
Autoimmune Hepatitis- Systemic Lupus Erythematosus Overlap Syndrome
Vijayram Reddy Malladi, Ahmed Al-Khazraji, Zhenghui Gordon Jiang, Daryl Lau
Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States
17.
Expression of Plasma Circulating MicroRNA (C-MicroRNAs) Changes with Different Collection/Storing Techniques Implication for Standardized Reporting Methods
Iuliana Shapira1, Paul Abrudescu1, Erica Testani1, Ameer Aboud1, Annette Lee2
1Medicine, SUNY Downstate, Brooklyn, New York, United States, 2Genomics and Genetics, Feinstein Institute for Medical Research, Manhasset, New York, United States
18.
Navigation Needs of Inner City Black Patient Population Undergoing Chemotherapy for Cancer
Devon Mckenzie, Sawsan Amireh, Uri Goldberg, Iuliana Shapira
Medicine, SUNY Downstate, Brooklyn, New York, United States
19.
Improved Access to Pediatric Specialty Care with Telemedicine
Rachel Hatcliffe1, Matthew J. Ledda1, Briana Kyne3, Craig Sable1,2, Audra Fain1, Gia Badolato1, Shireen Atabaki1,2
1Children's National Medical Center, Washington, District of Columbia, United States, 2The George Washington University School of Medicine, Washington, District of Columbia, United States, 3The University of Maryland School of Medicine, Baltimore, Maryland, United States
20.
The Effect of B-Hydroxybutyrate on Human Microglia: Implications for the Ketogenic Diet in Neurodegenerative Disorders
Lora J. Kasselman, Christine Chevalier, Juan Zhen, David Grossfeld, Aaron Pinkhasov, Irving Gomolin, Allison B. Reiss
Biomedical Research, NYU Winthrop Hospital, Mineola, New York, United States
21.
Direct Acting Antivirals In HCV Mono-Infection Compared To HCV/HIV Co-Infection in Community Care Setting.
Vijay Gayam, Mazin Khalid, Pavani Garlapati, Arshpal Gill, Muhammad Rajib HOSSAIN, Osama Mukhtar
Medicine, Interfaith Medical Center, Brooklyn, New York, United States
22.
Familial Leukemia: Examination of 84 Pedigrees
Matthew P. Blakley2, 1, Janice Dutcher1, Peter H. Wiernik1
1Cancer Research Foundation, Chappaqua, New York, United States, 2College of Human Ecology, Cornell University, Ithaca, New York, United States
23.
Is Cognitive Rest Following a Head Injury Associated with Prolonged Concussion Symptoms?
Jeremy M. Root, Jamil Madati, Matt Ledda, Kristen Breslin, Shireen Atabaki
Emergency Medicine, Children’s National Medical Center, Washington, District of Columbia, United States
24.
Microglia in a Hyperglycemic Environment Promote Alzheimer's Disease-Like Pathology through Cholingergic Synaptic Dysfunction and Increased Amyloid ? Production
Hirra A. Arain1, Heather A. Renna1, Lora J. Kasselman1, Aaron Pinkhasov3, Irving Gomolin4, Alan M. Jacobson1, Joshua DeLeon2, Melissa Fazzari5, Allison B. Reiss1,2
1Biomedical Research, NYU Winthrop Hospital, Mineola , New York, United States, 2Department of Medicine , NYU Winthrop Hospital, Mineola , New York, United States, 3Psychiatry , NYU Winthrop Hospital, Mineola, New York, United States, 4Geriatrics, NYU Winthrop Hospital, Mineola, New York, United States, 5Biostatistics, NYU Winthrop Hospital , Mineola, New York, United States
2:45 PM - 3:00 PM
BREAK
3:00 PM - 4:30 PM
Ask the AFMR Investigators
Moderators:
Akankasha Goyal MD, Albert Einstein College of Medicine, Bronx NY
Lora Kasselman, PhD, NYU Winthrop Hospital, Mineola NY

Table 1: Type 1 Diabetes
Siham Accacha, MD, NYU Winthrop Hospital, Mineola NY

Table 2: NIH Grant Writing
Amit Dey, NHLBI, NIH, Bethesda MD

Table 3: Abstract Writing & Journal Submission
Peter Wiernik, Cancer Research Foundation, Bronx NY
Joshua DeLeon, NYU Winthrop Hospital, Mineola, NY

Table 4: Leadership & Volunteering
MingMing Ning, MD, MMSc, Mass General Hospital/Harvard Medical School, Boston, MA
Alison Reiss, NYU Winthrop Hospital, Mineola NY

Table 5: Mentoring
Steven J. Crosby, MA, RPh, MA, College of Pharmacy & Health Sciences, Boston, MA

Table 6: Inflammation and Sepsis
Yutong Zhao, MD, PhD, University of Pittsburgh, Pittsburgh PA

4:30 PM - 4:45 PM
AWARD PRESENTATIONS Allison B. Reiss, MD, NYU Winthrop Hospital, Mineola NY
Chair, AFMR Eastern Section Council
  • Moderated Poster Competition
  • Eastern Region Scholars
5:00 PM
ADJOURN

Display Posters
DP1.
Large Bronchogenic Cyst
Theo D. Trandafirescu
Medicine, Mount Sinai Services, Queens Hospital Center, Flushing, New York, United States
DP2.
A Case of Hematologic Dysfunction and Idiopathic Dystonia in Hermansky-Pudlak Syndrome
Gagan Raju, Sandra Gomez
Internal Medicine, Nassau University Medical Center, Brooklyn, New York, United States
An Unusual Case of Gallbladder Cancer in a Young Male
Sandra Gomez Paz1, Shruti Patel2, Kaleem Rizvon2
1Internal Medicine, NUMC, East Meadow, New York, United States, 2Gastroenterology and Hepatology, NUMC, East Meadow, New York, United States
DP5.
A Case of Decompression Sickness Syndrome Presenting in the Limbs after Deep Sea Diving
Nashreen Anderson
Internal Medicine, Nassau University Medical Center, Brooklyn, New York, United States
DP6.
Exploring Abnormalities in Lung MicroRNAs in Idiopathic Pulmonary Fibrosis using Exhaled Breath Condensate
Nadia Pletukhina1, Lora J. Kasselman2, Steven H. Salzman1, Heather A. Renna2, Allison B. Reiss2, Priya Agarwala1
1Pulmonary and Critical Care Medicine, NYU Winthrop Hospital, Mineola, New York, United States, 2Biomedical Research, NYU Winthrop Hospital, Mineola, New York, United States
DP7.
Unique Presentation of Thrombotic Thrombocytopenic Purpura Flare with Normal Lactate Dehydrogenase and Haptoglobin
Angela Marcelino, Carol A. Luhrs
Hematology Oncology, SUNY Downstate Hospital, NY, New York, United States
DP8.
Indolent CNS Relapse in Adult T cell Lymphoma
Sparsha Kukunoor, Elvira Neculiseanu, Angela Marcelino
Hematology - Oncology, SUNY Downstate, Brooklyn, New York, United States
DP9.
Two Decades of Trends in Blood Stream Infections (BSI) in Advanced Malignancy Patients with Epithelial Barrier Disruption (EBD) Building the Case of Population Specific Studies
Michael Haddadin, Sandeep Singh, Swati Vishwanathan, Iuliana Shapira
Medicine, SUNY Downstate, Brooklyn, New York, United States
DP10.
Coccidioidomycosis of the Epididymis and Testis Presenting as a Testicular Mass
Nazanin Sheikhan, Arash Heidari, Shahab Hillyer
Internal Medicine, UCLA-Kern Medical Center, Woodland hills, California, United States
DP11.
Necrotizing Skin Infection Caused by Streptococcal Agalactiae: Case Study
Shane M. Hagen, Amina Chaudry, MD, Nick A. DiLoreto, James B. Lewis, Jr., MD
Department of Medicine, Memphis VAMC, Memphis, TN
DP12.
Checkpoint Inhibitors in Head and Neck Cancer: Current Status and Perspectives
Bachar Samra, Eric Tam, Babak Baseri, Iuliana Shapira
Hematology/Oncology, SUNY Downstate Medical Center, Brooklyn, New York, United States
DP13.
Epithelial Barrier Disruption (EBD) Is the Source of Blood Stream Infection (BSI) in Minority Inner-City Black Patients with Advanced Malignancies and High Burden of Co-Morbidities: Implication for Population Specific Studies
Michael Haddadin1, Josephine Anuforo2, Eric Tam1, Iuliana Shapira1
1Medicine, SUNY Downstate, Brooklyn, New York, United States, 2Medicine, St. John’s Episcopal Hospital, Far Rockaway, New York, United States
DP15.
A Rare Case of Gastric Plasmacytoma
Sandra Gomez Paz2, Gagan Raju2, Rabab Hajar1, Kaleem Rizvon1
1Gastroenterology and Hepatology, NUMC, East Meadow, New York, United States, 2Internal Medicine, NUMC, East Meadow, New York, United States
DP16.
Unexplained Hypokalemia with Paraparesis in Young Adult, Think Thyrotoxic Periodic Paralysis!
Mohammad K. Islam, Chandralekha Ashanghari, Luis Ruiz, Kaylee Shepherd
Internal Medicine, Texas Tech Univ HSC Amarillo, Amarillo, Texas, United States
DP17.
Improving Time to Hospital Admission from the Pediatric Emergency Department at a Large Academic Children’s Center
Hanae Fujii-Rios, Ted Kouo, Keith Kleinman, Lucas Falco, Amanda O'Halloran, Kameron Rogers, John Creagh, Julia Kim, Oluwakemi Badaki-Makun, Therese Canares
Pediatrics, Johns Hopkins, Baltimore, Maryland, United States