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AFMR Foundation

AFMR 2015 Eastern Regional Meeting

Program and Abstracts | Posters


WEDNESDAY, APRIL 15, 2015
Robert's Private Dining Room
5:00 PM - 6:00 PM
WELCOME RECEPTION
Light hors d'oeuvres and cocktail reception.

THURSDAY, APRIL 16, 2015
Ambassador Ballroom
7:00 AM
EASTERN MEETING REGISTRATION & CONTINENTAL BREAKFAST
7:30 AM - 8:30 AM
SYMPOSIUM 1: Update: Primary Immune Deficiency Disorders Associated with Chronic Rhinosinusitis and Malignancy
Moderators: Janice P. Dutcher, M.D.
Cancer Research Foundation, Bronx, NY

Iuliana Shapira, M.D.
Hofstra North Shore LIJ School of Medicine, Hempstead, NY

Chronic Rhinosinusitis, Good's Syndrome and CVID
Marianne Frieri, M.D., Ph.D., FACAAI, FAAAAI, Organizer
Professor of Medicine & Pathology SUNY, Stony Brook
Nassau University Medical Center, East Meadow, New York

Primary Immune Deficiency Disorders (PIDs) Associated Malignancies and Lymphoproliferative Diseases
Joseph A. Bellanti, M.D., FACAAI, FAAAAI
Professor of Pediatrics and Microbiology and Immunology
Director International Center for Interdisciplinary Studies of Immunology
Georgetown University, Washington, DC

8:45 AM - 9:00 AM
AFMR INTRODUCTION AND WELCOME
Peter H. Wiernik, M.D.
Chair, AFMR Eastern Region
9:00 AM - 10:50 AM
SCIENTIFIC SESSION I
Moderators: Oana Sandu, MD
Albert Einstein College of Medicine, Bronx, NY

Steven G. Coca, D.O., M.S.
Yale University School of Medicine, New Haven, CT
1.
Cytokine Airway Responses to Acute Rhinovirus Infection and Respiratory Morbidity in Severe Premature Children
Geovanny F. Perez1,2, Gustavo Nino1,2, Krishna Pancham1, Shehlanoor Huseni1, Amisha Jain1, Carlos Rodriguez-Martinez3, Diego Preciado2,4, Mary Rose2
1Pulmonary and Sleep Medicine, Children's National Medical Health Systems, Washington DC, United States. 2Center for Genetic Research Medicine, Children's National Health Systems, Washington DC, United States. 3Department of Pediatrics, School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia. 4Division of Pediatric Otorhinolaryngology, Departments of Surgery and Pediatrics, George Washington University School of Medicine and Health Sciences, Washington DC, United States.
2.
In Vivo Evidence in a Xenograft Model for Asthmatic Epithelium Driving Airway Remodeling
Sarah Ferrante1, Tillie-Louise Hackett2, John F. Engelhardt3, Jennifer L. Ingram4, Susan Reynolds5, Yulong Zhang3, Claire E. Hoptay1, Sarah E. Alcala1, Furquan Shaheen2, Ethan Matz1, Dinesh K. Pillai1, Robert J. Freishtat1
1Children's National Medical Center, Washington, DC, United States. 2UBC James Hogg Research Centre, Vancouver, BC, Canada. 3University of Iowa, Iowa City, IA, United States. 4Duke University, Durham, NC, United States. 5National Jewish Health, Denver, CO, United States.
3.
Vascular Inflammation in the Aorta is Related to Coronary Plaque Burden in Psoriasis
Taufiq Salahuddin1, Balaji Natarajan1, Mariana Selwaness2, Ahmed Sadek1, Martin Playford1, Julia Doveikis1, David Bluemke2, Nehal N. Mehta1
1National Heart, Lung and Blood Institute, Bethesda, MD, United States. 2National Institutes of Health Clinical Center, Bethesda, MD, United States.
4.
Immunosuppressive Drugs Mycophenolate Mofetil and Cyclosporin A: Disparate Effects on Atherogenic Lipid Accumulation in THP-1 Human Macrophages
Michael Salama, Iryna Voloshyna, Michael J. Littlefield, Isaac Teboul, Joshua De Leon, Steven E. Carsons, Joseph Mattana, Allison B. Reiss
Medicine, Winthrop University Hospital, Mineola, NY, United States.
5.
Obesity and Atherosclerosis: Exosome Effect on Cholesterol Efflux in THP-1 Human Macrophages
Ashley Barlev1, Iryna Voloshyna1, Sarah C. Ferrante2, Michael Salama1, Michael J. Littlefield1, Allison B. Reiss1, Robert J. Freishtat2
1Winthrop Research Institute, Winthrop University Hospital, Mineola, NY, United States. 2Children's National Medical Center, Washington, DC, United States.
6.
Characteristics of African American Children with Inadequate Calcium Intake
Leticia M. Ryan1, Janet Crane1, Courtney Sprouse2, Laura L. Tosi2
1Johns Hopkins University School of Medicine, Baltimore, MD, United States. 2Children's National Medical Center, Washington, DC, United States.
7.
The Impact of Perineural Invasion in Patients with Esophageal Adenocarcinoma Treated with Esophagectomy
K. Mehta, V. Bianco, A. Hamilton, W. E. Gooding, J. D. Luketich, A. Pennathur
Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
8.
Serum IGF1 and Insulin Resistance: Hepatic Steatosis and Metabolic Syndrome
Evan D. Siau, Louis F. Amorosa
Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
9.
Genetic Variation in Neuromedin U Influences Lean Body Mass and Bone Morphometry in Men
Elizabeth A. Hedges1, Courtney A. Sprouse2, Heather Gordish-Dressman5, Leticia M. Ryan3, Michael Liu1, Zachary Kendrick1, Elizabeth Dominic1, Jacqueline McKesey4, Eric Hoffman5, Joseph M. Devaney5, Laura L. Tosi5
1The George Washington University School of Medicine and Health Sciences, Washington, DC, United States. 2Children's National Medical Center, Washington, DC, United States. 3Johns Hopkins School of Medicine, Baltimore, MD, United States. 4Georgetown University School of Medicine, Washington, DC, United States. 5Children's Research Institute, Children's National Medical Center, Washington, DC, United States.
10.
High Neck Circumference is Associated with Poor Asthma Control
Lisa A. Maltz2, Ethan Matz1, Heather Gordish-Dressman2, Dinesh Pillai2, 3, 4, Stephen Teach3, 5, Simran Behniwal2, Nicole Certner2, Raman Marwah2, Yodit Tsegaye1, Robert Freishtat2, 3, 5
1George Washington University School of Medicine and Health Sciences, Washington, DC, United States. 2Department of Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC, United States. 3Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC, United States. 4Division of Pulmonary and Sleep Medicine, Children's National Health System, Washington, DC, United States. 5Division of Emergency Medicine, Children's National Health System, Washington, DC, United States.
11.
Effect of Metabolic Substrates on Intermittently Anoxic Peripheral Nerve
Melanie L. Wegener1, Mark M. Stecker2, Matthew Stevenson2
1Stony Brook University School of Medicine, Port Jefferson Station, NY, United States. 2Neuroscience, Winthrop University Hospital, Mineola, NY, United States.
10:50 AM - 11:05 AM
BREAK
11:05 AM - 11:20 AM
RESEARCH!AMERICA ADVOCACY WORKSHOP
"Your Role in Shaping Science Policy through Advocacy"
Anna Briseno
Senior Communications Specialist
Research!America
11:20 AM - 12:05 PM
6TH ANNUAL FORMER AFMR/AFCR PRESIDENT’S ADDRESS
Construction, Deconstruction and Reconstruction: An American History of Academic Medicine
Veronica M. Catanese, MD, MBA
Vice Dean and Dean for Academic Affairs
Dr. Leo A. Guthart Endowed Chair and Professor of Medicine
Hofstra North Shore-LIJ School of Medicine
12:05 PM - 1:35 PM
MODERATED POSTER LUNCH COMPETITION
Moderators: Ofek Hai, D.O.
SUNY Downstate Medical Center, Brooklyn, NY

Robert J. Freishtat, MD, MPH
Children's National Medical Center, Washington, D.C.
MP1.
Do Classically Activated M1 Macrophages Display Pro-Atherogenic Changes in Cholesterol Transport Proteins?
Megan B. Wallace1, 2, Iryna Voloshyna1, Isaac Teboul1, Michael J. Littlefield1, Joshua De Leon1, Allison B. Reiss1
1Medicine, Winthrop University Hospital, Mineola, NY, United States. 2Wellesley College, Wellesley, MA, United States.
MP2.
Perioperative Management of Cardiovascular Implantable Electronic Devices (CIEDs): An Analysis of Adherence to Guidelines
Eric J. Berkowitz, Alaeldin Eltom, Arber Kodra, Kabir Bhasin, Neil L. Coplan
Cardiovascular Medicine, Lenox Hill Hospital, New York, NY, United States.
MP3.
Diagnostic Cardiac Fellows: Do They Increase Radiation Exposure and Procedural Times
Ankita Sharma, Ramsey Joudeh, Molly Perini, George Fernaine
Internal Medicine, Lutheran Medical Center, Bayside, NY, United States.
MP4.
A Genetic Variant in the Gamma Glutamyl Carboxylase Gene Affects Bone Quality in a Pediatric African American Cohort
Jacqueline McKesey1,2,3, Courtney Sprouse2,3, Elizabeth Dominic2,3,4, Elizabeth Hedges2,3,4, Zachary Kendrick2,3,4, Michael Liu2,3,4, Leticia M. Ryan5, Joseph M. Devaney2,4, Laura L. Tosi3,4
1Georgetown University School of Medicine, Springfield, VA, United States. 2Center for Genetic Medicine, Children's National Health System, Washington, DC, United States. 3Orthopaedics and Sports Medicine, Children's National Health System, Washington, DC, United States. 4School of Medicine and Health Sciences, George Washington University, Washington, DC, United States. 5Johs Hopkin Children's Center, Baltimore, MD, United States.
MP5.
Clinical Characteristics of PFO Stroke in Pregnancy
Lei Chen1,2, Wenjun Deng2, Wickham Thomas R2, David McMullin D2, Lo Eng H2, Ferdinando S Buonanno2, Mingming Ning2
1Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. 2Neurology, Massachusetts General Hospital, Boston, MA, United States.
MP6.
Using Electronic Medical Record Data for Local Surveillance to Predict Hospitalization in Acute Asthma in the Pediatric Emergency Department.
Shilpa J. Patel1, Zuyi Wang2, Stephen J. Teach1, Robert J. Freishtat1, James Chamberlain1
1Emergency Medicine, Children's National Medical Center, Bethesda, MD, United States. 2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, United States.
MP7.
Characterization of Nasal Airway Microbiota During Rhinovirus Infection in Full Term and in Premature Infants
Geovanny F. Perez1,2, Marcos Perez-Losada2, Krishna Pancham1, Shehlanoor Huseni1, Anamaris Colberg-Poley2, Gustavo Nino1, 2
1Pulmonary and Sleep Medicine, Children's National Medical Center, Washington DC, United States. 2Center for Genetic Research Medicine, Children’s National Health System, Washington DC, United States.
MP8.
Pregnancy Outcomes Following PFO Related Stroke
Lei Chen1,2, Wenjun Deng2, Thomas R Wickham2, David McMullin D2, Lo Eng H2, Ferdinando S Buonanno2, Mingming Ning2
1Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. 2Neurology, Mass General Hospital, Boston, MA, United States.
MP9.
Gender Differences in Children with Forearm Fractures
Leticia M. Ryan1, Janet Crane1, Courtney Sprouse2, Laura Tosi2
1Johns Hopkins University School of Medicine, Baltimore, MD, United States. 2Children's National Medical Center, Washington, DC, United States.
MP10.
PathoScope: Integrating Microbiome Characterization and Host Gene Expression in Pediatric Asthma
Marcos Perez-Losada1,2, Douglas Mansell1, Eduardo Castro Nallar2, William E. Johnson3, Keith A. Crandall2, Robert J. Freishtat1
1Children's Research Institute, Children's National Medical Center, Washington, DC, United States. 2Computational Biology Institute, George Washington University, Ashburn, VA, United States. 3Boston University School of Medicine, Boston, MA, United States.
MP11.
Obesity Derived Adipocyte Exosomes Alter TGF? Signaling Gene Expression in Lung Epithelium
Gurpreet Phull, Justin Wang, Sarah Ferrante, Humaira Mubeen, Eussra El-Magbri, Evan Nadler, Monica Hubal, Robert Freishtat, Dinesh Pillai
Pulmonology, Children's National Medical Center, Washington, DC, United States.
MP12.
Asthmatic Airway Fibroblasts: Obese Exosome Exposure Up-Regulates TGF? Receptor Signaling
S. Ferrante1, J. Ingram2, E Nadler1, M Hubal1, J Seo3, M Giri1, D Jung3, D Pillai1, R Freishtat1
1Children's National Medical Center, Washington, DC, United States. 2Duke University, Durham, NC, United States. 3Seoul National University, Seoul, Korea (the Republic of).
MP13.
Lupus: An unusual presentation
Omar A. Tolaymat
Internal Medicine, University of Florida Jacksonville, Jacksonville, FL, United States.
MP14.
The Correlation of TIMI Risk Scores with Extent of Coronary Artery Disease in a Multi-Ethnic Patient Population Presenting with Non-ST Elevation Myocardial Infarction
Ali A. Torbati, Joyce Chou, Nyla Malik, Preston Garnes, Francois Dufresne
Medicine, Lutheran Medical Center, New York, NY, United States.
1:35 PM - 3:35 PM
SCIENTIFIC SESSION II
Moderators: Cherry Wongtrakool, M.D.
Emory University School of Medicine, Atlanta, GA

Peter H. Wiernik, M.D.
Cancer Research Foundation, Bronx, NY
12.
Mitotic Asynchrony Induces a Pro-Inflammatory State in Airway Epithelium
S Alcala1, A Benton1, A Watson1, E Reeves2, J Damsker2, Z Wang1, K Nagaraju1, M Rose1, E Hoffman1, R Freishtat1
1Center of Genetic Medicine, Children's National Medical Center, Washington, DC, United States. 2Reveragen Biopharma, Bethesda, MD, United States.
13.
Young Children with History of Prematurity have Impaired Airway Antiviral IFN? Responses to Human Metapneumovirus Compared to Respiratory Syncytial Virus.
Krishna Pancham1, Geovanny Perez1, Shehlanoor Huseni1, Amisha Jain1, Bassem Kurdi2, Carlos E. Rodriguez-Martinez3, Diego Preciado4, Mary C. Rose5, Gustavo Nino1
1Department of Pulmonary Medicine, Childrens National Medical Center, Washington, DC, United States. 2Pediatrics, Childrens National Medical Center, Washington, DC, United States. 3National University of Colombia, Bogota, Colombia. 4Department of Otolaryngology, Childrens National Medical Center, Washington, DC, United States. 5Childrens National Medical Center, Washington, DC, United States.
14.
Vitamin D Repletion Reduces Adipose Tissue Fibrosis and Improves Insulin Sensitivity in obese insulin-resistant Humans
Akankasha Tiwari, Kehao Zhang, Michelle Carey, Meredith Hawkins, Preeti Kishore
Endocrinology, Albert Einstein College of Medicine, Bronx, NY, United States.
15.
Role of Adenosine A2A and A3 Receptors in Macrophage Polarization: Link between Inflammation and Lipid Accumulation
Isaac Teboul, Iryna Voloshyna, Michael Littlefield, Joseph Mattana, Joshua De Leon, Allison Reiss
Medicine, Winthrop University Hospital, Mineola, NY, United States.
16.
Hypoglycemic Counterregulation in Humans is Impaired by Opioid Receptor Activation.
Michelle Carey, Harry Shamoon, Nora Tomuta, Ilan Gabriely, Meredith Hawkins
Medicine-Endocrinology, Albert Einstein College of Medicine, Bronx, NY, United States.
17.
Plasma and Tissue MicroRNA Patterns Discriminate Malignancy in Patients with Benign Ovarian Masses: Enrichment Analysis of Genetic Pathways
Iuliana Shapira1,2, Janaki Parameswaran2, Michaela Oswald2, Annette Lee2
1Medicine, Jacobi Medical Center/Hofstra North Shore LIJ School of Medicine, Hempstead, NY, United States. 2Feinstein Institute for Medical Research, Manhasset, NY, United States.
18.
Initial Pediatric Asthma Severity Score in the Emergency Department Predicts Hospitalization.
Shilpa J. Patel, Sabah F. Iqbal, Stephen J. Teach, James Chamberlain
Emergency Medicine, Children's National Medical Center, Bethesda, MD, United States.
19.
Positive Predictive Values of Positive D-Dimer Levels in Venous Thromboembolic Events Diagnosed by CT Angiography, Venous Duplex, and V/Q Scan
Ankita Sharma1, Naveen Sablani1, Natalie Pavelock1, Oksana Genzer1, Preston Garnes2, George Fernaine1
1Internal Medicine, Lutheran Medical Center, Brooklyn, NY, United States. 2Clinical Research, Lutheran Medical Center, Brooklyn, NY, United States.
20.
Interaction of Epigenetics and TGF Beta Pathway in Renal Cell Carcinoma- A Potential Therapeutic Target with Hypomethylating Agents
Niraj Shenoy, Amit Verma
Internal Medicine, Albert Einstein College of Medicine, Bronx, NY, United States.
21.
Heart Failure Discharge Education: How Well are We Educating Our Patients? A Patient Quality and Safety Initiative.
Bryan Doherty, Tarak Rambhatla, Evan Levine, Neil Coplan
Lenox Hill Hospital, New York, NY, United States.
22.
Does an Upright T Wave in Lead V1 Predict Left Anterior Descending Artery Lesion and/or a Left Circumflex Artery Lesion on Cardiac Catheterization?
Naveen Sablani1, Drew Murray2, Praveen Chatani2, Young Lee2, Bonnie Simmons1, Soheila Talebi3, Roger Chirurgi3, George Fernaine1, Getaw W. Hassen1, 3
1Internal Medicine, Lutheran Medical Center, Brooklyn, NY, United States. 2St. George's University School of Medicine, Grenada, Grenada. 3New York Metropolitan Hospital, New York, NY, United States.
23.
Comparative Effect of Ustekinumab and Adalimumab on Expression of Leptin and Leptin Receptor in THP-1 Human Macrophages
Jessica S. Mounessa1,2, Allison B. Reiss1,2, Steven E. Carsons1,2, Iryna Voloshyna1
1Winthrop University Hospital, Great Neck, NY, United States. 2Medicine, SUNY Stony Brook School of Medicine, Stony Brook, NY, United States.
3:35 PM - 3:50 PM
BREAK
3:50 PM - 5:05 PM
SYMPOSIUM 2: Resveratrol: Hope or Hype?
Moderators: Leticia M. Ryan, M.D., MPH
Johns Hopkins Children's Center, Baltimore, MD

Michael Schivo, MD, MAS
UC Davis Medical Center, Sacramento, CA

Atheroprotective Effects of Resveratrol in Models of Systemic Lupus Erythematosus
Allison B. Reiss, M.D.
Winthrop University Hospital, Mineola, NY

Effects of Resveratrol on Glucose Tolerance and Endothelial Function in Humans with Prediabetes
Jill Crandall, M.D.
Albert Einstein College of Medicine, Bronx, NY

Effects of Resveratrol on Skeletal Muscle Glucose Metabolism and Adipose Tissue “Browning” in Humans
Meredith Hawkins, M.D., Organizer
Albert Einstein College of Medicine, Bronx, NY

Oana Sandu, M.D., Organizer
Albert Einstein College of Medicine, Bronx, NY
5:05 PM - 6:05 PM
AFMR PRESIDENTIAL PLENARY SESSION (SCIENTIFIC SESSION III)
Moderators: Armand A. Krikorian, M.D. FACE
UIC/Advocate Christ Medical Center, Chicago, IL

Amir A. Zeki, MD, MAS, AFMR President-Elect
UC Davis Medical Center (CCRBM), Sacramento, CA
24.
A Prospective Observational Quality Assurance Study Of Cost-Effectiveness Of TSH Testing in the Inpatient Setting
Panagiotis J. Vlachostergios, Katerina G. Oikonomou, Lindsay Zielinski, Michelle Li, Francois Dufresne
Internal Medicine, Lutheran Medical Center, Brooklyn, NY, United States.
25.
Review and Identification of Neural Networks Tools Used in Cancer and Cardiovascular Risk Models
Oana Sandu1, Iulian Nastac2
1Albert Einstein College of Medicine, Bronx, NY, United States. 2UPB, Bucharest, Romania.
26.
The Role of Gut Microbiome in the Development of Food Allergy
Grace Covelli1,2,3, Iuliana Shapira3, Jaime H. Kiehm2, Annette Lee1, Punita Ponda1,2
1Feinstein Institute for Medical Research, Manhasset, NY, United States. 2Allergy and Immunology, Hofstra North Shore LIJ School of Medicine, Manhasset, NY, United States. 3Jacobi Medical Center, Bronx, NY, United States.
27.
Variability in Antibiotic Use in Low-Acuity Pediatric Emergency Department Patients
Kristen Breslin, Kaynan Doctor, James Chamberlain, Deena Berkowitz
Division of Emergency Medicine, Children's National Medical Center, Washington, DC, United States.
28.
Insulin Resistance Determines Severity of Vascular Inflammation by 18-Fluorodeoxy Glucose PET-CT in Psoriasis
Balaji Natarajan 1, Taufiq Salahuddin1, Martin Playford1, Peter Herscovitch2, Nehal Mehta1
1Division of Inflammation and Cardiometabolic Disease, National Heart Lung and Blood Institute, Bethesda, MD, United States. 2PET Department, NIH Clinical Center, Bethesda, MD, United States.
29.
Proteomic study of Middle Ear Effusions: Implication of Neutrophil Extracellular Traps (NETs) in Otitis Media
Stéphanie Val1, Kristy Brown2, Marian Poley1, Samita Goyal2, Yetrib Hathout2, Mary Rose2, Diego Preciado1
1Sheihk Zayed Institute, Children's National Medical Center, Washington, DC, United States. 2Center for Genetic Medicine, Washington, DC, United States.
6:05 PM - 6:20 PM
AWARD PRESENTATIONS
Poster Competition
Eastern Region Scholars
6:20 PM
ADJOURN
*AFMR Eastern Region Scholar Award Recipient
**AFMR Henry Christian Award Recipient
+Junior Physician Investigator Award Recipient
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