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AFMR Foundation

AFMR EASTERN REGION - ANNUAL MEETING
Wednesday, April 9, 2008
Washington Marriott Hotel
Washington, DC


WEDNESDAY, APRIL 9, 2008
11:00 am - 4:00 pm
REGISTRATION
1:00 pm - 2:00 pm
Posters to be set in session room
2:00 pm - 5:30 pm
Display Posters available for viewing
2:00 pm - 2:05 pm
INTRODUCTION AND WELCOME
James Coromilas, MD, Chair, Eastern Region
American Federation for Medical Research

James C. Oates, MD, President American Federation for Medical Research
2:05 pm - 3:45 pm
SCIENTIFIC SESSION I: Oral Presentations
(Nine 11 Minute Presentations - 8 to present and 3 to discuss)

Moderators: James Coromilas, MD and James Oates, MD
1.
VITAMIN D INSUFFICIENCY IN AFRICAN AMERICAN CHILDREN WITH FOREARM FRACTURES
L.M. Ryan, R. Freishtat, J. Wright, J. Chamberlain, Emergency Medicine, Children's National Medical Center, Washington, DC; L.M. Ryan, J. Wright, J. Chamberlain, Research Center for Health Services and Community Research, Children's National Medical Center, Washington, DC; C. Brandoli, L. Tosi, Orthopaedics and Sports Medicine, Children's National Medical Center, Washington, DC; R. Freishtat, E. Hoffman, Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC; J. Wright, Child Health Advocacy Institute, Children's National Medical Center, Washington, DC
2.
A LOW SOLUBLE CD40 LIGAND LEVEL EXCLUDES PATIENTS WITH HIGH-RISK ANGIOGRAPHIC FEATURES BETTER THAN THAT OF TROPONIN I
V.S. Gadi, N. Nerella, D. Thekkoott, B. Malik, J. Shani, E. Lichstein, Cadiology, Maimonides Medical Center, Brooklyn, NY
3.
Clinical, genetic, and quality of life studies of autosomal recessive congenital ichthyosis in 104 patients
S. Farasat,1 M.H. Wei,1 B. Ahvazi,1 D.J. Liewehr,1 S.M. Steinberg,1 S.J. Bale,2 P. Fleckman,3 J.R. Toro,1; 1. National Institutes of Health, Bethesda, MD; 2. GeneDx, Inc, Gaithersburg, MD; 3. University of Washington, Seattle, WA
4.
ATHEROGENICITY OF COX INHIBITION IS ENHANCED IN THE PRESENCE OF LUPUS SERUM AND ABROGATED BY PROSTAGLANDIN D2 OR E2
S. Edelman, E. Pone, S. Carsons, E. Belilos, L. Bonetti, K. Belostocki, G. Rosenblum, A.B. Reiss, Rheumatology, Winthrop University Hospital, Mineola, NY; E.S. Chan, Rheumatology, New York University, New York, NY
5.
AGE-ATTENUATION OF THE LIPOPROTEIN-ASSOCIATED RISK OF AORTIC VALVE CALCIFICATION (AVC) IN THE MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA)
D.S. Owens, R. Katz, E. Johnson, J.L. Probstfield, R. Kronmal, K.D. O'Brien, University of Washington, Seattle, WA; D.M. Shavelle, J. Takasu, M.J. Budoff, LA Biomedical Research Institute, Los Angeles, CA;J.R. Crouse, J.J. Carr, Wake Forest University, Winston-Salem, NC
6.
PLATELETS AS CYTOTOXIC MEDIATORS IN SEPSIS: PLATELET GRANZYME B INDUCES LYMPHOCYTE APOPTOSIS
R. J. Freishtat 1, 2, 3, J. Natale 4, J. S. Cohen 1, 3, B. Mojgani 2, A. S. Benton 2, W. M. Ngor 2, M. Bradbury 2, C. Bunaj 2, E. P. Hoffman 2, 3; 1. Division of Emergency Medicine, Children's National Medical Center, Washington, DC, USA. 2. Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, USA. 3. School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA. 4. Department of Pediatric Critical Care, University of California at Davis, Sacramento, CA, USA.
7.
HOSPITAL WATER: A POSSIBLE SOURCE OF HEALTHCARE-ASSOCIATED INFECTIONS IN BONE MARROW TRANSPLANT RECIPIENTS
J.S. Cervia, B. Farber, D. Armellino, Division of Infectious Diseases, North Shore University Hospital, Manhasset, NY; J.S. Cervia, F.P. Canonica, G.A. Ortolano, Pall Medical, East Hills, NY
8.
Association of a Common Variant of the Signal Transducer and Activator of Transcription 4 (STAT4) Gene with Primary Sjögren's Syndrome
B.D. Korman, J. Le, D. Kastner, E. Remmers, Genetics and Genomics Branch, National Institute of Arthritis Muskuloskeletal and Skin Diseases, Bethesda, MD; M. Alba, I. Alevizos, N. Nikolov, G. Illei, Sjögren's Syndrome Clinic, National Institute of Dental and Craniofacial Research, Bethesda, MD; M. Alba, I. Alevizos, N. Nikolov, G. Illei, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, Bethesda, MD; J. Smith, Office of the Clinical Director, National Eye Institute , Bethesda, MD; B.D. Korman, Clinical Research Training Program, National Institutes of Health, Bethesda, MD
9.
A TIMP-1-NUCLEATED NETWORK IS CRITICAL FOR THE BRONCHIAL EPITHELIAL RESPONSE TO TOBACCO SMOKE IN ASTHMA
R. J. Freishtat 1, 2, 3, A. S. Benton 2, Z. Wang 2, 4, E. P. Hoffman 2, 3; 1. Division of Emergency Medicine, Children's National Medical Center, Washington, DC, MD, USA. 2. Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, USA. 3. School of Medicine and Health Sciences, The George Washington University, Washington,DC, USA. 4. The Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic University, Arlington, VA, USA.
3:45 pm - 4:30 pm
SCIENTIFIC SESSION II: Moderated Poster Presentations
(Eight 5 Minute Presentations - 3 to present and 2 to discuss)

Moderators: James C. Oates, MD and Michael J. McPhaul, MD
MP1.
PEDIATRIC MOCK CODES: IMPROVING RESIDENT RESUSCITATIONS
P. Zaveri, D. Friedman, K. O'Connell, Emergency Medicine and Trauma Center, Children's National Medical Center, Washington, DC
MP2.
POPCORN CALCIFICATION IN OSTEOGENESIS IMPERFECTA
A.A. Obafemi, J.C. Marini, Bone and Extracellular Matrix Branch, NICHD/NIH, Bethesda, MD; A.A. Obafemi, UMDNJ-New Jersey Medical School, Newark, NJ
MP3.
RELATION OF OBSTRUCTIVE CORONARY ATHEROSCLEROSIS TO DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS
C. Assal, J. Shirani, B. Martin, A. Armstrong, M. Diehl, D. Torretti, J. Blankenship, Cardiology, Geisinger Medical Center, Danville, PA
MP4.
USE OF SEQUENTIAL BIOCHEMOTHERAPY (BCT) IN PATIENTS (PTS) WITH MALIGNANT MELANOMA (MM): RESULTS OF A PHASE II TRIAL
P.R. Bojanapally, V. Rusciano, P. Wiernik, J. Dutcher, Internal Medicine, Our Lady Of Mercy Medical Center, Bronx, NY; P. Wiernik, J. Dutcher, Internal Medicine, New York Medical College, Bronx, NY
MP5.
NEW ONSET ATRIAL FIBRILLATION DEVELOPING IN MEDICAL INPATIENTS
S.X. Chen, K. Amir, R. Bobba, E. Arsura, Medicine, Richmond University Medical Center, Staten Island, NY
MP6.
ELEVATION OF SERUM CREATINE PHOSPHOKINASE IN MEDICAL INPATIENTS
S.X. Chen, K. Amir, R. Bobba, E. Arsura, Medicine, Richmond University Medical Center, Staten Island, NY
MP7.
A CROSS-SPECIES ANALYSIS OF PLATELET GENE EXPRESSION IN SEPSIS SHOWS DYSREGULATION OF THE INNATE IMMUNE CYTOKINES IL-1 AND TNFa
A. S. Benton 1, W. M. Ngor 1, B. Mojgani 1, R. J. Freishtat 1, 2, 3; 1. Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, USA. 2. Division of Emergency Medicine, Children's National Medical Center, Washington, DC, USA. 3. School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
MP8.
SINGLE NUCLEOTIDE POLYMPORHISMS IN TNFAIP3, TRAF1/C5, AND PTPN22 REGIONS SHOW ASSOCIATION WITH CAUCASIAN SYSTEMIC LUPUS ERYTHEMATOSUS BUT NOT WITH KOREAN RHEUMATOID ARTHRITIS
B.D. Korman, D. Kastner, E. Remmers, Genetics and Genomics Branch, National Institute of Arthritis Muskuloskeletal and Skin Diseases, Bethesda, MD; H. Lee, S. Bae, Department of Rheumatology, Hanyang University College of Medicine and the Hospital for Rheumatic Diseases, Seoul, SOUTH KOREA; H. Lee, P. Gregersen, Robert S Boas Center For Genetics & Genomics, Feinstein Institute for Biomedical Research, Manhassett, NY; L. Criswell, Department of Rheumatology, University of California San Francisco, San Francisco, CA; B.D. Korman, Clinical Research Training Program, National Institutes of Health, Bethesda, MD
4:30 pm - 5:30 pm
JOINT PLENARY SESSION - AFMR AND CLINICAL RESEARCH FORUM
Changing Models of Biomedical Research: Implications for Clinical Investigators & AHCs

William F. Crowley, Jr., MD
5:30 pm - 6:30 pm
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